复方紫花地丁对鸭大肠杆菌MIC逆转效果的影响  

Study on the reversal effect of Herba Violae compound prescription on antibioticresistant duck E.coli

作　　者：余建国[1] 朱楼英 严晗光[1] 王科健 

机构地区：[1]金华职业技术学院,浙江金华321007 [2]金华市食品药品检验所,浙江金华321000 [3]金华市科健动物医院,浙江金华321000

出　　处：《中兽医医药杂志》2013年第6期23-26,共4页Journal of Traditional Chinese Veterinary Medicine

基　　金：金华市重点科技项目(2012-2-013)

摘　　要：以恩诺沙星人工诱导鸭大肠杆菌耐药菌株,原始菌株和诱导株经不同浓度的复方紫花地丁溶液处理,检测其MIC及菌体药物蓄积浓度。结果表明,经复方紫花地丁溶液处理的菌株,MIC显著降低,且与紫花地丁溶液呈浓度依赖关系。研究结果提示,一定浓度的紫花地丁溶液可以逆转鸭大肠杆菌的耐药性。Artificially induced resistant strains of duck E. coli by enrofloxacin, different concentrations of Herba Viol compound prescription was used to treat the original strains and induced strains, and the MIC and drug accumulation were tested. The results showed that the MIC of the strains treated by compound solution was marked decreased, and a concentration-dependent manner was presence with compound solution, Research suggested that a certain concentration of Herba Violae compound prescription can the antibiotic-resistance of duck E.coli.

关 键 词：恩诺沙星 紫花地丁 MIC 耐药性 

分 类 号：S853.7[农业科学—临床兽医学]