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作 者:张艳梅
机构地区:[1]郑州市中医院,河南郑州450000
出 处:《中医学报》2013年第12期1796-1798,共3页Acta Chinese Medicine
基 金:郑州市2012年度科技发展计划(编号:20120906)
摘 要:目的:探讨穴位埋线联合口服麻杏石甘茶治疗小儿咳嗽变异性哮喘近期止咳及远期防复发的疗效及其作用机理。方法:100例患者按随机数字表法分为两组,治疗组50例采用穴位埋线联合口服麻杏石甘茶治疗,咳嗽期间口服麻杏石甘茶,咳嗽停止即可停药,最长不超过14 d。对照组50例口服孟鲁司特钠咀嚼片,急性发作期给予特布他林压缩雾化吸入,咳嗽停止即可停药,最长不超过14 d。两组均以3个月为1疗程。治疗观察近期及远期疗效、治疗前后外周血嗜酸性粒细胞直接计数(EOS)及血清免疫球蛋白IgE的变化。结果:①治疗组有效率为98%,对照组有效率为90%,两组比较差异有显著统计学意义(P<0.05);②治疗组近期及远期疗效优于对照组;③治疗后治疗组外周血嗜酸性粒细胞直接计数(EOS),IgE水平明显低于对照组(P<0.01),提示治疗组均明显优于对照组。结论:穴位埋线联合口服麻杏石甘茶治疗小儿咳嗽变异性哮喘疗效显著,不良反应小。Objective:To investigate the recent relieving cough and long-term preventing recurrence efficacy and action mechanism of in- fantile cough variant asthma treated by acupoint catgut embedding combined with oral administration Ma Xing Shi Gan Tea. Methods: 100 patients were randomly divided into two groups. The treatment group of 50 cases were given acupoint catgut embedding combined with oral administration Ma Xing Shi Gan Tea. Oral administration Ma Xing Shi Gan Tea during the period of cough, hnd stopped medi- cating once the coughing stopped, and the maximum medication period of 14 days. The control group of 50 cases wer given oral adminis- tration Montelukast Sodium Chewable Tablets. The patients were given aerosol inhalation Compression Terbutaline in acute attack peri- od. Stopped medicating once the coughing stopped, and the maximum medication period of 14 days. 3 months for one course of treatment of the two groups. Observed the recent and long-time efficacy, Eosinophils of peripheral blood and serum immunoglobulin IgE before and after treatment. Resuhs:①The total effective rate of treatment group was 98%, and the control group was 90%, the difference between the two groups was statistical significant(P 〈 0.05) ;② The recent and long-term efficacy of the treatment group was superior than that of the control group; ③After treatment, the levels of Eosinophils of peripheral blood and serum immunoglobulin IgE of the treatment group were significantly lower than that of the control group(P 〈 0.01 ), which prompted that the effects of treatment group were signifi- cantly better than the control group. Conclusion:Acupoint catgut embedding combined with oral administration Ma Xing Shi Gan Tea in treating infantile cough variant asthma has less side effects and reliable curative effect.
分 类 号:R256.12[医药卫生—中医内科学]
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