黄芩汤提取工艺研究  

Study on Extraction Technology of Huangqin Decoction by Orthogonal Design

作　　者：赵明伟[1] 孙耀志[2] 高松[2] 陈杰[1] 左静静[1] 李响[1] 

机构地区：[1]河南中医学院,河南郑州450046 [2]河南宛西制药股份有限公司,河南南阳473000

出　　处：《中医学报》2013年第12期1862-1864,共3页Acta Chinese Medicine

基　　金：国家重大新药创制项目(编号:2013ZX095-08105)

摘　　要：目的:优选黄芩汤的提取工艺。方法:以方中黄芩苷含量、芍药苷含量和干膏率为指标,采用L9(34)正交试验法,优化黄芩汤的提取工艺。结果:黄芩汤最佳提取工艺为加水量为其处方量药材的10倍,煎煮3次,每次1 h。结论:该工艺稳定可行,重现性良好。Objective：To optimize the extraction process of Huangqin Decoction. Methods：Using the orthogonal design, the content of ba- icalin,paeoniflorin and the dried decocting rates were selected as indexs to optimize the extraction process of Huangqin Decoction. Re- suits：The best extraction process of Huangqin Decoction was obtained as following ：10 times of water, extraction for 3 times and 1 hour for each time. Conclusion：The optimized process is stable and good reproducibility.

关 键 词：黄芩汤 黄芩苷 芍药苷 提取工艺 正交试验 

分 类 号：R284.2[医药卫生—中药学]