氢化诺卜基甲酰胺类化合物的合成与结构表征  

The Synthesis and Structural Characterization of Hydronopylformamide Compounds

作　　者：刘艳[1] 肖转泉[2] 卢平英[3] 陈金珠[1] 王宗德[1] 范国荣[1] 

机构地区：[1]江西农业大学林学院,江西南昌330045 [2]江西师范大学化学化工学院,江西南昌330022 [3]江西农业大学图书馆,江西南昌330045

出　　处：《江西师范大学学报（自然科学版）》2013年第5期515-518,共4页Journal of Jiangxi Normal University(Natural Science Edition)

基　　金：国家林业公益性行业科研专项经费(201304602);广西林产化学与工程重点实验室(GXFC11-07)资助项目

摘　　要：由氢化诺卜基溴(RBr)与镁反应制成格氏试剂,再与二氧化碳反应并经稀酸分解合成了氢化诺卜基甲酸(RCO2H),后者与亚硫酰氯反应制成酰氯(RCOCl),再分别与氨、二甲胺、二乙胺、二异丙胺、六氢吡啶、吗啉等反应合成了6种氢化诺卜基甲酰胺类化合物,各化合物都用IR、1H NMR、13C NMR与MS进行了结构表征.Grignard reagent was prepared through the Grignard reaction of hydronopyl bromine and magnesium, and hydronopylformic acid was synthesized from the decompose reaction of diluted acid with carbon dioxide. Then hydro- nopylformyl chloride was obtained from the reaction of hydronopylformic acid and thionyl chloride. Finally, six kinds of hydronopylformamide compounds were synthesized from the reaction of hydronopylformyl chloride with ammonia, dimethylamine, diethylamine, diisopropylamine, hexahydropyridine and morpholine respectively. The structures of the products were characterized by IR, 1H NMR, 13C NMR and MS methods.

关 键 词：氢化诺卜基溴 Grignard反应 氢化诺卜基甲酸 氢化诺卜基甲酰胺 结构分析 

分 类 号：O621[理学—有机化学] TQ351[理学—化学]