多巴胺联合硝普钠治疗顽固性心力衰竭的临床疗效研究  

Effect of Dopamine Combined with Nitroprusside in the Treatment of Refractory Heart Failure

作　　者：杨昭[1] 李莺[1] 黄文军[1] 林晓清[1] 欧珏[1] 吴建云[1] 许辉[1] 

机构地区：[1]江西省萍乡市人民医院B超室,337000

出　　处：《实用心脑肺血管病杂志》2013年第12期70-71,共2页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

基　　金：江西省萍乡市指导性科技计划项目(萍科字[2013]87号:09)

摘　　要：目的评价多巴胺联合硝普钠治疗顽固性心力衰竭的临床疗效。方法选取2010年1月—2012年8月我院收治的顽固性心力衰竭患者150例,将其随机分为对照组和观察组,各75例。对照组给予常规治疗,观察组在此基础上给予多巴胺联合硝普钠治疗。结果观察组总有效率为93.3%(70/75),高于对照组的74.7%(56/75)(P<0.05);治疗后观察组收缩压、舒张压及心率均低于对照组,左室射血分数(LVEF)高于对照组(P<0.01)。结论多巴胺联合硝普钠治疗顽固性心力衰竭临床疗效显著,能有效改善心功能。Objective To evaluate the effect of dopamine combined with nitroprusside in the treatment of refractory heart failure. Methods 150 patients with refractory heart failure admitted to our hospital between January 2010 and August 2012 were selected, and they were randomly divided into control group and observation group, 75 cases in each. Patients in the con- trol group were given conventional treatment, while patients in the the observation group were given dopamine and nitroprusside based on the conventional treatment. Results The total efficacy of observation group was 93.3% （70/75） , higher than that of control group of 74. 7% （56/75） （P 〈 0. 05 ） ; After treatment, the systolic blood pressure, diastolic blood pressure and heart rate of observation group were lower than those of control group, ventricular ejection fraction （LVEF） was higher than that of control group （ P 〈 0.01 ）. Conclusion It is with good clinical effect of dopamine combined with nitroprusside in the treatment of refractory heart failure, which can improve heart function.

关 键 词：多巴胺 硝普钠 顽固性心力衰竭 治疗结果 

分 类 号：R541.6[医药卫生—心血管疾病]