妊娠早期甲状腺功能与促绒毛膜性腺激素的关系  

The Study of relationship between the function of Thyroid and HCG in early pregnancy

作　　者：黄绘[1] 张华[1] 叶秀兰[2] 

机构地区：[1]贵阳市妇幼保健院,550003 [2]贵州省人民医院内分泌科,贵阳550002

出　　处：《贵州医药》2000年第12期714-715,共2页Guizhou Medical Journal

摘　　要：目的了解妊娠早期甲状腺功能与促绒膜促毛性腺激素 (HCG)的关系。方法用放免或免放方法测定 39例正常孕妇妊娠早期血清FT3 、FT4 、TSH及HCG水平。结果妊娠早期血清FT3 、FT4 在正常范围偏高 ,血清TSH水平正常偏低 ,且有 30 77%低于正常范围 ,血清hGC水平较非妊娠育龄妇女显著升高 ;HGC与FT3 、FT4 呈正直线相关关系 (r=0 30 2 ,P <0 0 5 ,及r=0 498,P <0 0 1) ,而与TSH呈负直线相关关系 (r =0 331,P <0 0 5 )。结论提示妊娠早期hCG对垂体—甲状腺轴有一定的调节作用。Objective To evaluate the relationship between the function of thyroid and HCG in early pregnancy. Methods In 39 health women in early pregnancy, the serum FT 3,FT 4, TSH and HCG were measured with radioimmuno assay or immunoradiometric assay.Results The serum FT 3 and FT 4 were relatively high, but all in normal range in early pregnancy. The serum TSH below the reference range were 30.77% in early pregnancy. The serum HCG were highter than nonpregnancy wornan. A significant negative correlation between TSH and HCG levels was demonstrated and a significant positive correlation between HCG and FT 3 and FT 4. Conclusion HCG may be as role of regulation of pituitary thvroid axis in early pregnancy.

关 键 词：妊娠早期 甲状腺功能 促绒毛膜性腺激素 

分 类 号：R714.147[医药卫生—妇产科学]