复方党参胶囊的质量研究  

Studies of quality standard about Fufang Dangshen capsules

作　　者：李海池[1] 李菁[2] 张超[1] 沈雪梅[1] 

机构地区：[1]广东药学院,510006 [2]广州中医药大学,510006

出　　处：《天津中医药大学学报》2013年第4期225-228,共4页Journal of Tianjin University of Traditional Chinese Medicine

基　　金：广东省中山市科技局基金项目(2010H015)

摘　　要：[目的]建立复方党参胶囊的质量控制方法。[方法 ]采用薄层色谱法（TLC）对制剂中党参、白术、香附、黑芝麻进行定性鉴别;采用紫外分光光度法测定制剂中总多糖含量。[结果]TLC法可专属性地鉴别党参、白术、香附和黑芝麻,且特征斑点圆整清晰,阴性对照无干扰。含量测定结果显示,总多糖在60.96~304.8μg范围线性关系良好,r=0.999 5（n=8）,平均加样回收率为99.79%（RSD 1.98%,n=6）。[结论]所建立的方法简便可行、专属性强、重复性好,可有效控制复方党参胶囊的质量。[Objective] To study and establish the quality control methods for Fufang Dangshen capsules.[Methods] The method of TLC was used to identify Radix Codonopsis,Rhizoma Atractylodis Macrocephalae,Rhizoma Cyperi and Sesami Semen Nigrun. The content of polysaccharose was determined by ultraviolet spectrophotometric method. [Results] Four herbal drugs were well identified by TLC,the spots were clear,round and without interference. Quantitative analysis of ultraviolet spectrophotometric method showed that the linear range of determination polysaccharose was 60.96~304.8 μg,r=0.999 5（n=8）. The average recovery of determination was99.79% and the RSD was 1.98%（n=6）. [Conclusion] This method is simple,reliable and high specific with good repeatability,and can be used for the quality control of Fufang Dangshen capsules.

关 键 词：复方党参胶囊 质量控制 薄层色谱法 紫外分光光度法 

分 类 号：R285.5[医药卫生—中药学]