眼科医院抗菌药物使用的调查分析  

Investigation and analysis of the use of antimicrobial drugs in ophthalmic hospital

作　　者：刘美欣[1] 郭嫒[2] 黄婷婷[2] 陈曦[1] 王雁[1] 

机构地区：[1]天津市眼科医院天津市眼科学与视觉科学重点实验室,天津300020 [2]天津医科大学临床医学院药学系,天津300270

出　　处：《中华医院感染学杂志》2013年第23期5789-5791,共3页Chinese Journal of Nosocomiology

基　　金：国家自然科学基金资助项目(81178073)

摘　　要：目的了解眼科医院抗菌药物的使用和存在问题,为促进抗菌药物的合理应用提供依据。方法采用回顾性调查方法,按照《全国抗菌药物临床应用专项整治活动方案》规定的指标统计2011年抗菌药物应用各项数据(DDD,DDDs,AUD:抗菌药物使用强度等),随机抽取眼科医院2011年出院患者病历120份,对住院患者抗菌药物使用进行调查分析。结果门诊患者抗菌药物处方数分布占1.88%,住院患者抗菌药物使用率为54.10%,Ⅰ类切口预防使用抗菌药物的使用率为48.21%,住院治疗性应用抗菌药物患者病原学检查率为57.15%。结论医院抗菌药物使用基本合理,但预防用药不规范,应在重点科室严格控制Ⅰ类切口预防使用抗菌药物,自2011年下半年预防使用抗菌药物指标趋于合理。OBJECTIVE To investigate the use and the existing problems of antimicrobial drugs in hospital, and provide the basis for promoting the rational application of antimicrobial drugs. METHODS According to the targets specified in Rectification Program of Clinical Application of Antimicrobial Drugs in China, all the data of antimi-crobial drug use in 2011 were counted （including DDD, DDDS, AUD： antimicrobial use density, etc. ） using the method of retrospective investigation. And 120 prescriptions of discharged patients in this hospital were selected randomly so as to investigate and analyze the use of antimicrobial drugs. RESULTS The ratio of prescriptions with antimierobial drugs for outpatients was 1.88% while 54. 10% for inpatients. The use frequency of antimicrobial chemoprophylaxis for A class incision was 48.21%, and 57.15 % of the patients who took therapeutic application of antimicrobial drugs in hospital received etiology examination. CONCLUSION The use of antimicrobial drugs is basically rational except for chemoprophylaxis. Furthermore, the supervision should be focus on the usage of anti- microbial chemoprophylaxis of A class incision in key department. And the targets of antimicrobial chemoprophy-laxis tended to be more rational since the second half of 2011.

关 键 词：抗菌药物 DDD DDDS 合理应用 

分 类 号：R978.1[医药卫生—药品]