碳酸利多卡因用于气管导管气囊内对气管插管后咽痛的影响  

The impact of filling endotracheal tube cuff with lidocaine carbonate on postoperative sore throat in general anaesthesia

作　　者：周炜[1] 刘灿[1] 鲁美静[1] 郭文俊[1] 金孝岠[1] 

机构地区：[1]皖南医学院附属医院麻醉科,安徽省芜湖市241001

出　　处：《临床麻醉学杂志》2013年第11期1051-1053,共3页Journal of Clinical Anesthesiology

摘　　要：目的评价碳酸利多卡因用于全麻患者气管导管气囊内对气管插管后咽痛的影响。方法择期拟在全麻下行下腹部手术的患者64例，年龄32～74岁，体重45-78kg，采用随机数字表法将患者均分为四组：麻醉诱导气管插管后分别向气囊内缓慢注入空气6～10ml（A组）、生理盐水6～10ml（S组）、2％利多卡因6～10ml（L组）、1．73％碳酸利多卡因6～10ml（CL组）。记录拔管后30min（T1）、1h（T2）、2h（T3）、3h（T4）、24h（T5）的咽痛评分及患者对导管留置的耐受程度。结果T1～T5时L组和CL组的咽痛评分均明显低于A组（P〈0．05）；T1～T3时CL组咽痛评分明显低于L组（P〈0．05）。CL组围拔管期气管导管耐受程度1～2级患者例数明显多于A组（P〈0．05）。结论1．73％碳酸利多卡因用于全麻患者气管导管气囊内，可以减轻气管导管刺激引起的术后咽痛，是一种较为有效的方法。Objective To evaluate the impact of filling endotracheal tube cuff with lidocaine carbonate on sore throat in general anesthesia. Methods Sixty-four ASA I or Ⅱ patients, aged 32- 74 yr, weighing 45-78 kg, undergoing elective abdominal surgery under general anesthesia were randomly divided into four groups（n= 16 each）. 6-10 ml of air, saline, 2% lidocaine or 1.73% lidocaine carbonate was filled in endotracheal tube cuff respectively in group A, group S, group L and group CL. The endotracheal tube tolerance and sore throat scores were recorded 30 min （T1）, 1 h （T2）, 2 h （T3）, 3 h （T4） and 24 h （T5） after extubation. Results The sore throat scores were significantly lower in groups L and CL than those in group A at T1-T5 （P〈0. 05）. In addition, the sore throat scores in group CL were lower than those in group L at T1-T3 （P〈0.05）. The patients of endotracheal tube tolerance grade of 1-2 were greater in group CL than that in group A（P〈0.05）. Conclusion Filling endotracheal tube cuff with 1.73% lidocaine carbonate can relieve sore throat in patients during general anesthesia.

关 键 词：利多卡因 气管插管 应激 

分 类 号：R614[医药卫生—麻醉学]