不同体位下气腹对妇科手术患者S100β蛋白和MMSE评分的影响  

The effect of different position on the level of S100β and MMSE score in female patients undergoing gynecological laparoscopy

作　　者：李陆军[1] 史宏伟[2] 孙振全[1] 曹雪莲[1] 赵灵芝[1] 季娟[1] 

机构地区：[1]南京市中西医结合医院麻醉科,210014 [2]南京市第一医院麻醉科

出　　处：《临床麻醉学杂志》2013年第11期1064-1066,共3页Journal of Clinical Anesthesiology

基　　金：南京市卫生局科研项目(QYK11145)

摘　　要：目的研究不同Trendelenburg体位下气腹对妇科手术患者S100β蛋白和MMSE评分的影响。方法妇科腹腔镜手术患者60例，ASAI或Ⅱ级，随机均分为两组，Trendelenburg体位角度分别为20°组（T20组）和40°组（T40组）。记录麻醉诱导后（T2）、体位10min（R）、放气10min后（T3）和术后1h（rr4）的血清S100β蛋白含量，记录术前、术后1、6、12、24h的MMSE评分。结果T1～T4时两组血清S100β蛋白含量组间组内差异均无统计学意义。两组不同时点MMSE评分差异无统计学意义。结论Trendelenburg体位角度对妇科腹腔镜手术患者S100β蛋白和MMSE评分无明显影响。Objective To compare the effect of different angle of Trendelenburg position on the level of S100β and MMSE score in female patients undergoing gynecological laparoscopy. Methods A total of 60 female patients, ASA physical status I or Il , were randomly divided into two groups （n = 30）, T20 group and T40, S100β level were recorded at several different time points, including after induction（T1 ）, 10 min after Trendelenburg position（T2）, 10 min after exclude abdominal insufflation （T3）, 1 h after operation（T4）. MMSE score was recorded including before induction and 1,6,12,24 hours after operation. Results The results showed that the S100β level had no differences in two groups of patients at T1-T4. The MMSE score at 1,6, 12,24 h after operation had no differences compared with preoperation. Conclusion Different angles of Trendelenburg position might have no effect on the level of S100β and MMSE score.

关 键 词：S100Β蛋白 CO2气腹Trendelenburg体位 认知功能障碍 

分 类 号：R614[医药卫生—麻醉学]