经导管去肾交感神经术治疗代谢综合征的现状与展望  

Present State and Perspectives of Catheter-based Sympathetic Renal Denervation in Treating Metabolic Syndrome

作　　者：赵志钢[1] 祝之明[1] 

机构地区：[1]第三军医大学大坪医院高血压内分泌科全军高血压代谢病中心重庆市高血压研究所,重庆400042

出　　处：《心血管病学进展》2013年第6期725-727,共3页Advances in Cardiovascular Diseases

基　　金：国家973项目:"环境代谢因素致高血压机制及其干预措施的研究"(2012CB517805)

摘　　要：作为一种新的治疗顽固性高血压的治疗方法,经导管去肾交感神经术已被证实可以有效降低交感神经活性、去甲肾上腺素溢出以及血压。交感神经激活与代谢综合征关系密切,几个临床试验已经显示经导管去肾交感神经术对于改善葡萄糖代谢和胰岛素敏感性有潜在益处。这项技术能否用于治疗代谢综合征值得进一步研究。Being a novel therapeutic technique for the treatment of patients with resistant hypertension, the catheter-based sympathetic renal denervation （RDN） has been shown to effectively reduce sympathetic nerves activity, norepinephrine spillover as well as blood pressure. A close associations exist between sympathetic activation and metabolic syndrome. The results of several clinical trials indicate that RDN has potential benefits in improving glucose metabolism and insulin sensitivity. Further studies are need to investigate the capability of renal sympathetic denervation to treat metabolic syndrome.

关 键 词：经导管去肾交感神经术 代谢综合征 潜在益处 

分 类 号：R589[医药卫生—内分泌]