理想心血管健康行为与因素对全因和心血管病因死亡的影响  

Association of ideal cardiovascular health behaviors and factors with all-cause and cardiovascular disease mortality

作　　者：戚常春 刘妍[2] 陈朔华[3] 张彩凤[2] 杨慧[4] 姚涛[5] 刘星[6] 刘小雪[2] 韩红锋[2] 吴寿岭 

机构地区：[1]开滦总医院建设分院心内科,河北唐山063000 [2]河北联合大学研究生学院 [3]开滦医疗集团重症医学科 [4]河北联合大学附属开滦医院急诊科 [5]开滦医疗集团林西医院内科 [6]河北联合大学附属开滦医院体检中心 [7]心内科

出　　处：《中华高血压杂志》2013年第11期1033-1039,共7页Chinese Journal of Hypertension

摘　　要：目的探讨理想心血管健康行为与因素对全因和心血管病因死亡的影响。方法采用前瞻性队列研究，入选2006-07-2007-10开滦集团健康查体的职工95429人（男性76109人，女性19320人），年龄18．0～98．0（5I．5±12．5）岁，随访观察死亡情况；依据美国心脏协会（AHA）定义的理想心血管健康行为和因素，采用Cox比例风险模型分析心血管健康行为和因素的死亡风险比及95％CI。结果在平均4．02年的随访期间，死亡1843例（心血管病因死亡597例）。有5～7个理想心血管健康行为与因素者占9．0％，其中有7个理想健康行为和因素者占0．1％。Cox比例风险模型分析发现，随着理想心血管健康行为与因素个数的增加，全因和心血管病因死亡呈下降趋势。以有≤1个理想心血管健康行为和因素者为参照，有≥5个理想健康行为与因素者发生全因死亡和心血管病因死亡的风险分别降低31％及42％（分别校正后OR0．69，95％C10．55～0．86，OR0．58，95％C10．89～0．86）。结论随着理想心血管健康行为与因素个数的增加，全因死亡和心血管病因死亡呈下降趋势。Objective To explore the impact of ideal cardiovascular health behaviors and factors on mortality from all causes and cardiovascular diseases. Methods Prospective cohort study method was used in our study. 95 429 workers （including 76 109 males and 19 320 females） who had participated in 2006-07-2007-10 Kailuan health ex amination without insufficient information for the cardiovascular health metircs were recruited. The age ranged from 18.0 to 98.0 （ 51.5 ±12.5） years. All workers were observed the occurrence of death. According to the AHA definition of ideal cardiovascular health behaviors and factors, Cox proportional hazards regression was used to calculate hazard ratios and 95% confidence intervals for baseline health behaviors and factors. Results During a median follow-up of 4.02 years, 1843 deaths （597 deaths resulting from cardiovascular diseases） occurred. Only 9.0% of the study cohort had 5-7 ideal cardiovascular health behaviors and factors. Only 0.1% of study cohort had all the ideal cardiovascular health behaviors and factors. Cox proportional hazards regression showed that the risks of mortality from all causes and cardiovascular diseases were reduced with the increase in the number of ideal health behaviors and factors. Compared with participants who had ≤1 ideal cardiovascular metric, those who met 5-7 metrics had a reduction of 31% （adjusted OR 0.69,95% CI 0. 55-0.86） in the risk of all cause mortality and 42%（adjusted OR O. 58,95% CI 0. 39-0.86） in the risk of mortality from cardiovascular diseases. Conclusion The risks of mortality from all causes and cardiovascular diseases were reduced, with the increase in the number of ideal health behaviors and factors.

关 键 词：理想心血管健康行为和因素 死亡率 队列研究 

分 类 号：R54[医药卫生—心血管疾病]