多沙唑嗪治疗高血压病的疗效观察  

The efficiency of doxazosin in patients with essential hypertension

作　　者：丁昌玲[1] 李喜梅[1] 

机构地区：[1]北京航空航天大学医院,100083

出　　处：《航空航天医药》2000年第4期196-198,共3页Aerospace Medicine

摘　　要：目的 :评价多沙唑嗪的降压疗效和安全性。方法 :4 1例高血压病人随机分成二组 :试验组A(服多沙唑嗪 ) ,对照组B(服特拉唑嗪 ) ,进行为期 4周的治疗观察。结果 :A组总有效率 86% ,服药 4周后平均收缩压 (SBP)和舒张压 (DBP)分别下降了 15 5mmHg和 12 8mmHg ,B组总有效率85% ,SBP和DBP下降的幅度为 14 0mmHg和 13 0mmHg。两组总有效率无显著性差异。结论 :多沙唑嗪是一种安全有效的抗高血压药物。OBJECTIVE:To estimate the efficiency and safety of doxazosin. METHODS:Forty one cases with essential hypertension were divided randomly into two groups: trial A (used doxazosin) and control B (used terazosin). Treatment lasted for 4 weeks. RESULTS:Total effective rate was 86% in A group and 85% in B group. SBP and DBP reductions in A group were 15 5mmHg and 12 8mmHg and in B group 14 0mmHg and 13 0mmHg. There was no significant difference in total effective rate between the two groups. CONCLUSION:Doxazosin is effective and well tolerated in treating hypertensive patients.

关 键 词：多沙唑嗪 特拉唑嗪 高血压 药物治疗 比较 

分 类 号：R544.105[医药卫生—心血管疾病] R972.4[医药卫生—内科学]