高血压患者左心室肥厚与QT离散度增大  

Left ventricular hypertrophy and QT dispersion increase in patients with hypertension

作　　者：许智韬[1] 王玮[1] 田青[1] 翟彪[1] 

机构地区：[1]昆明市第一人民医院心内科,650011

出　　处：《中华心律失常学杂志》2000年第4期276-278,共3页Chinese Journal of Cardiac Arrhythmias

摘　　要：目的　进一步探讨高血压左心室肥厚及左心室质量增大与 QT离散度 (QTdispersion,QTd)改变的关系。方法　采用 12导联心电图同步描记及心脏超声检查等方法对 94例原发性高血压患者 [男性 40例 ,女性 5 4例 ,年龄 (5 9.9± 11.2 )岁 ]和 11例正常人 [男性 4例 ,女性 7例 ,年龄 (5 2 .8±16 .9)岁 ]作 QTd及左心室肥厚、左心室质量检测分析。结果　高血压左心室肥厚组 ( 组 ,n=6 2 ) QTd较非肥厚组 ( 组 ,n=32 )以及正常对照组 ( 组 ,n=11)均明显增大 (P<0 .0 1～ 0 .5 0 ) ,QTd与左心室质量呈正相关 (r=0 .47,P<0 .0 1)。结论　原发性高血压左心室肥厚、左心室质量增大可使 QTd明显增大 ,具有心室肌复极不均一。Objective To study the relationship between hypertensive left ventricular hypertrophy and QT dispersion (QTd). Methods QTd and left ventricular thickness and mass were measured by 12 lead synchronously recording ECG and echocardiogram in 94 primary hypertension patients [male=40,female=54,age=(59 9±11 2) years] and 11 normal subjects [male=4,female=7,age=(52 8±16 9) years]. Results The QTd of the patients ( n= 62) with ventricular hypertrophy was significantly larger than that of the patients ( n =32) without ventricular hypertrophy and the normal subjects ( P< 0 01).QTd were directly related to ventricular mass ( r=0 5,P <0 01). Conclusion QTd may be increased significantly by hypertensive ventricular hypertrophy and ventricular mass increasing which would form the functional basis for ventricular asynchronous repolariz[WT5”,6BZ]ation,and increase the potential risk of leading to reentrant ventricular arrhythmias and sudden death.

关 键 词：QT离散度 左心室肥厚 心电图 高血压 

分 类 号：R544.1[医药卫生—心血管疾病]