梅毒感染流行的新趋势探讨  

The new trend of syphilis epidemic

作　　者：杨延龙[1] 

机构地区：[1]随州市中心医院检验科,441300

出　　处：《国际检验医学杂志》2013年第B12期20-21,共2页International Journal of Laboratory Medicine

摘　　要：目的分析输血前筛检患者梅毒结果模式及年龄、性另q的分布情况，从而了解目前本地区梅毒感染状况及流行特征。方法对4500例标本同时用TP-Ab（ELISA法）和TRUST进行检测，并对阳性标本用TPPA进行确证试验。结果共检出梅毒共118例，其中显性梅毒18～50岁，男性21例，阳性率0．85％，女性34例，阳性率1．7％，（U=6．139，P〈O．05）男女之比有显著性差异，女性比男性高；50-80岁，男性25例，阳性率1．1％，女性10例，阳性率0．5％（U=3．978，P〈O．05）男女之比有显著性差异，男性比女性高。潜伏梅毒18~50岁，男性8例，阳性率0．3％，女性6例，阳性率0．3％，（U=0．033，P〉0．05）男女之比无显著性差异；50~80岁，男性lO例，阳性率0．4％，女性4例，阳性率0．19％，（U=1．584，P〉0．O5）男女之比无差异j合计18～50岁男性梅毒患者29例，阳性率为1．2％；女性梅毒患者40例，阳性率2．0％（U=4．548，P〈O．05，；男女之比有显著性差异，女性比男性高；50-80岁男性患者35例，阳性率1．4％；女性梅毒患者14例，阳性率0．69％（U=5．587，P〈O．05）；男女之比有显著性差异，男性比女性高。先天梅毒1d至3岁10例，阳性率0．22％，经检查其父母均为显性梅毒或／和潜伏梅毒感染者。结论患者从高危人群向普通人群转化，为预防和避免院内感染，掌握当前患者感染情况和流行特征，有助于进一步采取措施，控制疫情发展。Objective To analyze the distribution of syphilis screening before transfusion patients age,gender and the pattern,so as to understand the infection situation of local area and epidemiological characteristics of syphilis. Methods 4 500 patients were examined by TP-Ab（ELISA） and TRUST were detected,and the positive samples were confirmed by TPPA test. Results A total of 118 cases of syphilis, the dominant syphilis 18-50 years old, male 21 eases, the positive rate was 0.85%, female 34 cases, the posi- tive rate was 1.7% （U=-6. 139,P〈0.05）, the ratio of male and female have significant difference, higher in females than in males; 50-80 years old,25 male patients, the positive rate was 1.1M, 10 cases of female, the positive rate was 0.5% （U= 3. 978, P〈 0.05）, the ratio of male and female have significant difference, higher in men than in women. Latent syphilis 18-50 years old, 8 male patients, the positive rate was 0.3 %, 6 cases of women, the positive rate was 0.3 N, （U= 0. 033,P〉0. 05） the gender ratio of no significant difference;50-80 years old, 10 male patients, the positive rate was 0.4% ,4 cases of women, the positive rate was 0.19 M （U= 1. 584, P〉0.05）, the ratio of male and female no difference;total 18-50 year-old male 29 cases of syphilis patients, the positive rate was 1.2% ; 40 cases of female, patients with syphilis, the positive rate was 2 % （U= 4. 548, P〈0.05） ; the ratio of male to female was significant difference,higher in women than men;men aged 50-80 patients with 35 eases,the positive rate of 1, 4 % ; 14 cases of female patients with syphilis,the positive rate was 0.69 %（U= 5. 587, P〈0.05） ;the ratio of male to female was signifi- cantly higher in men than in women. Congenital syphilis 1 days-3 years 10 casea,the p0aitive rate waa O. 22% ,after checking their parents were dominant syphilis or / and latent syphilis infection. Conclusion Patients with transformed from high-risk groups to the general population,to prevent and avoid nosocomial infection,grasp

关 键 词：患者 梅毒 显性梅毒 潜伏梅毒 

分 类 号：R759.1[医药卫生—皮肤病学与性病学]