红细胞膜带3蛋白及膜流动性在病理状态下的变化(英文)  

The changes of band 3 protein and membrane fluidity in pathologic condition

作　　者：崔晓波[1] 傅国辉[1] 姜晓姝[1] 赵炜明[2] 高旭[2] 卢远清[3] 

机构地区：[1]哈尔滨医科大学病理生理学教研室 [2]哈尔滨医科大学病理生化教研室 [3]哈尔滨医科大学附属第二医院血液科,黑龙江哈尔滨150086

出　　处：《哈尔滨医科大学学报》2000年第6期396-398,共3页Journal of Harbin Medical University

摘　　要：目的　研究带 3蛋白与红细胞膜流动性的关系及其在病理状态下的改变。方法　对血液病及高血压患者红细胞膜带 3蛋白相对含量、红细胞膜流动性及血浆MDA分别进行了测定。结果　血液病患者红细胞膜带 3蛋白相对含量和膜流动性较对照组显著降低。而血浆MDA含量较对照组显著升高。结论　病理状态下 ,膜流动性的降低与带 3蛋白的相对含量减少有关。Objective To study the relationship between band 3 protein and membrane fluidity.Methods The relative content of human band 3 protein,the membrane fluidity of erythrocyte and the plasma MDA were measured in normal and patients with hypertension and hemotologic disease.Results The membrane fluidity and the relative content of band 3 protein of erythrocyte from patients reduced,while the MDA level increased.Conclusion In pathological conditions,the reduced membrane fluidity concern with band 3 protein.

关 键 词：红细胞膜 带3蛋白 膜流动性 血液病 高血压 

分 类 号：R552.02[医药卫生—血液循环系统疾病] R544.102[医药卫生—内科学]