雌激素对阴道神经作用的研究进展  

How estrogen work on vagina nerves:recent research development

作　　者：李婷[1] 陈曦[1] 张渺[1] 

机构地区：[1]北京大学第一医院妇产科,北京100034

出　　处：《中国性科学》2013年第12期38-42,共5页Chinese Journal of Human Sexuality

摘　　要：阴道自主和感觉神经在女性性反应中起关键作用,阴道神经支配及功能的改变与绝经后阴道症状密切相关。大量实验研究证实,雌激素能够促进神经发育、再生、抗细胞凋亡、抗氧化、改善记忆和认知功能。但雌激素对阴道自主神经、感觉神经分布的影响目前尚未得出定论。此外在阴道神经功能作用的方面,雌激素可提高会阴区振动、触觉和压力觉敏感性,还能降低痛觉敏感性。雌激素对阴道自主和感觉神经分布及功能的影响,需要进一步研究证实。Adverse vaginal symptoms in postmenopausal women may be largely attributed to the changes of neurological distribution and the function of the vaginal autonomic and sensory nerves, which are essential in female sexual responds. A series of tests and studies have elucidated that estrogen could promote the growth and regeneration of nerves, exert anti - apoptosis and the antioxidation effect, as well as ameliorate memory and recognition. However, the potential impacts of estrogen on autonomic and sensory innervations of the vagina remain controversial. In the respect of the function of vaginal nerves, estrogen can not only improve the pressure/touch perceptions of perineum, but also can reduce nociceptive sensitivity. The potential impacts of estrogen on autonomic and sensory innervations and function of the vagina call for further study.

关 键 词：雌激素 自主神经 感觉神经 阴道 神经保护 神经分布 功能 

分 类 号：R711.7[医药卫生—妇产科学]