黄酮类化合物抗心肌缺血再灌注损伤的相关机制研究进展  

Related mechanism's research progress of flavonoids against myocardial ischemia-reperfusion injury

作　　者：陈秋红[1] 李钦[1] 杨伟俊 赵吟[1] 张信岳[1] 

机构地区：[1]浙江省医学科学院药物研究所,杭州310013 [2]新疆维吾尔自治区药物研究所,乌鲁木齐830004

出　　处：《中国临床药理学杂志》2013年第12期958-960,共3页The Chinese Journal of Clinical Pharmacology

基　　金：国家自然科学基金地区科学基金资助项目(81160527)

摘　　要：黄酮类化合物是一类在植物中广泛分布的多酚化合物,具有抗氧化、抗炎、扩张血管、抑制心律失常及抗血小板聚集等多种与心血管保护作用相关的药理活性。本文就其抗心肌缺血再灌注损伤的相关机制进行综述。Flavonoids is a kind of polyphenol compound,which widely distributed in a variety of plants and have many pharmacological activities associated with cardiovascular protection,such as antioxidation,anti-inflammatory,expansion blood vessel,inhibition arrhythmia,antiplatelet aggregation,etc. In this paper,the related mechanism against myocardial ischemia-reperfusion injury were summarized.

关 键 词：黄酮类化合物 缺血再灌注 机制 

分 类 号：R285.6[医药卫生—中药学] R972[医药卫生—中医学]