噻托溴铵联合肺康复措施对稳定期慢阻肺患者肺动脉压力和生活质量的影响  

Effect of Tiotropium combined pulmonary rehabilition on pulmonary hypertension and quality of life for patients with chronic obstructive pulmonary disease in stable phase

作　　者：毕见涛[1] 鞠贞会[1] 徐向英[1] 王艳萍[1] 韩炜[1] 张秀婵[1] 

机构地区：[1]山东省荣成市人民医院呼吸科,264300

出　　处：《中国医疗前沿》2013年第20期11-13,共3页China Healthcare Innovation

摘　　要：目的探讨噻托溴铵联合肺康复措施对中、重度慢阻肺合并肺动脉高压患者的疗效。方法将71例临床缓解期的中、重度慢阻肺合并肺动脉高压患者分为观察组35例和对照组36例,对照组行肺康复措施6个月,观察组在此基础上接受噻托溴铵干粉吸入,比较两组患者6min步行距离、间接肺动脉收缩压、生活质量评分。结果观察组患者6min步行距离、间接肺动脉收缩压、生活质量评分方面优于对照组,差异有统计学意义(P<0.01)。结论噻托溴铵联合肺康复措施对稳定期中、重度慢阻肺合并肺动脉高压患者有明显效果,可增加患者舒适度,降低肺动脉压力、改善患者生活质量。Objective To observe effect of tiotropium combined pulmonary rehabilition on patients of stable chronic obstructive pulmonary disease complicated with pulmonary hypertention. Methods A total of 71 patients of pulmonary function inⅡ-Ⅲ stable COPD complicated with pulmonary hypertension were recruited. The were divided into observation group（n=35） and control group（n=36）, the patients in control group received pulmonary rehabilitation measures, the observation group in addition to receiving tiotropium inhalation, after 6 months of intervention. Comparing the two group of patients with 6min walking distance, the systolic pulmonary artery pressure and quality of life. Results The distance of 6min walk, the systolic pulmonary artery pressure and quality of life in the observation group than the control group, the difference was statistically significant（P 〈0.01）. Conclusion For patients of stable COPD complicated with pulmonary hypertension, inhaled tiotropium dry power combined with pulmonary rehabilitaton, can reduce pulmonary artery systolic pressure, improve the symptoms of the disease, improve the quality of life.

关 键 词：噻托溴铵 肺疾病 慢性阻塞性 血压 肺动脉 康复 生活质量 

分 类 号：R563.9[医药卫生—呼吸系统]