芹灵冲剂质量稳定性的研究  

Studies on the Stability of Qinling Granules

作　　者：曹文斌[1] 陈红艳 杨新波 黄正明 王志超 

机构地区：[1]中国人民解放军北京军医学院药理教研室,北京100071 [2]中国人民解放军总后勤部卫生部药品仪器检验所,北京100071

出　　处：《解放军药学学报》2000年第6期308-311,共4页Pharmaceutical Journal of Chinese People's Liberation Army

摘　　要：目的 :考察芹灵冲剂在常温和高温、高湿环境下的稳定性。方法 :从高温高热 ,恒温恒湿 ,留样考察 3个方面 ,研究了芹灵冲剂的质量稳定性 ,用硝酸铝显色法测定总黄酮含量。结果 :常温下放置 2年 ,芹灵冲剂质量检查和卫生检查结果符合标准 ,恒温恒湿放置 3个月 ,产品黄酮含量未降低。高温加速实验结果显示 ,在 90～ 12 0℃范围内 ,随着温度的升高 ,黄酮含量下降 ,t(2 5℃ ) 0 .9　　　 =3 .72 (a)。结论 :芹灵冲剂在Aim To study the stability of Qinling Granules (QG).Methods The stability of QG under three conditions is studied in high temperature (from 90 to 120℃),in stalole relative humidity of 75% for 3 months,and in room temperature for 2 years.The content of total flavone of QG was determ ined by spectrophotometry.Results QG was stable at room temperature within 2 years.The content of total flavone of QG was reduced at high temperature,t (25℃) 0.9 =3.72(a).Conclusion:QG was stable at room temperature within 2 years.

关 键 词：芹灵冲剂 黄酮 稳定性 

分 类 号：R286.0[医药卫生—中药学]