多糖类药物提取及分离分析  

Extraction and Separation of Polysac Charides

作　　者：王玉 郑欣 唐宝珠 

机构地区：[1]广东省深圳市人民医院药学部,广东深圳518020

出　　处：《中国药物经济学》2013年第6期36-38,共3页China Journal of Pharmaceutical Economics

摘　　要：目的对多糖类药物的提取与分离方法和效果进行分析探讨,为今后的药物分析工作提供可靠的参考依据。方法提取方法有溶剂提取法、酸提取法、碱提取法、超临界流体萃取法;分离方法包括超滤法、沉淀法、柱层析法以及色谱法。结果通过上述提取分离方法能够获得多糖成分。结论近几年多糖类药物的药理作用已经受到了高度的重视,使得多糖类药物的提取与分离技术也得到了良好的发展。Objective The polysaccharides extraction and separation method and effect analysis, analytical work to provide a reliable reference basis for future drug. Methods The extraction with solvent extraction, acid extraction, alkali extraction by supercritical fluid extraction, separation methods include; ultrafiltration method, precipitation method, column chromatography and chromatography. Results The method could polysaccharide obtained by the extraction and separation. Conclusion Pharmacological effects in recent years polysaccharide drugs has got more and more attention, the technology of extraction and separation of polysaccharides has also been a good development.

关 键 词：多糖类药物 提取方法 分离纯化 研究 

分 类 号：R284.2[医药卫生—中药学]