A functional approach toward xerogel immobilization for encapsulation biocompatibility of Rhizobium toward biosensor  

作　　者：Pooja Arora Sunita Sharma Sib Krishna Ghoshal Neeraj Dilbaghi Ashok Chaudhury 

机构地区：[1]Department of Bio and Nano Technology, Guru Jambheshwar University of Science and Technology, Hisar-125001, Haryana, India [2]Light and Matter Physics Group, Raman Research Institute, Bangalore, India [3]Physics Department, University Teknologi of Malaysia, Malaysia

出　　处：《Frontiers in Biology》2013年第6期626-631,共6页生物学前沿（英文版）

摘　　要：Sol-gel derived silica has tremendous applications as a biocompatible scaffold for the immobilization of cells. The use of xerogel as a matrix in the blueprint of biosensors is an appealing proposition due to several inimitable characteristics of xerogels, primarily because of their high porous nature, amendable pore size, and exceptionally large internal surface area. Morphological （X-Ray Diffraction and Thermogravimmetric Analysis） and optical （Fourier Transform Infrared and UV-Vis absorption） studies of the silica matrices with entrapped Rhizobial （Rz） structure of the biomaterial has been made. Temporal and concentration dependent studies were conducted for impregnated samples; it showed that the response time for the new biosensor for determining the concentration of Rz is less than 20 min. In this work, first time a novel avenue to create a generic approach for the fabrication of biosensor has been created.Sol-gel derived silica has tremendous applications as a biocompatible scaffold for the immobilization of cells. The use of xerogel as a matrix in the blueprint of biosensors is an appealing proposition due to several inimitable characteristics of xerogels, primarily because of their high porous nature, amendable pore size, and exceptionally large internal surface area. Morphological （X-Ray Diffraction and Thermogravimmetric Analysis） and optical （Fourier Transform Infrared and UV-Vis absorption） studies of the silica matrices with entrapped Rhizobial （Rz） structure of the biomaterial has been made. Temporal and concentration dependent studies were conducted for impregnated samples; it showed that the response time for the new biosensor for determining the concentration of Rz is less than 20 min. In this work, first time a novel avenue to create a generic approach for the fabrication of biosensor has been created.

关 键 词：BIOSENSOR Fourier Transform Infrared spectroscopy （FTIR） RHIZOBIUM Thermo Gravimmetric Analysis （TGA） sol-gel XEROGEL X-Ray Diffraction （XRD） 

分 类 号：TQ174.75[化学工程—陶瓷工业] TP212.3[化学工程—硅酸盐工业]