护理干预对围生期心肌病患者脑钠肽水平的影响  

Effect of nursing intervention on serum brain natriuretic peptide levels in patients with peripartum cardiomyopathy

作　　者：梁婷[1] 李明[1] 尹丽娟[1] 

机构地区：[1]四川省医学科学院四川省人民医院,四川成都610072

出　　处：《中国医药导报》2014年第1期143-145,共3页China Medical Herald

摘　　要：目的探讨护理干预对围生期心肌病患者脑钠肽水平的影响及临床意义。方法选取2007年1月～2012年12月期间在四川省人民医院心内科住院并诊断围生期心肌病患者60例为研究对象．随机分为干预组（30例）和对照组（30例）。两组患者人院后均给予常规抗心衰治疗及护理。干预组在常规治疗、护理基础上根据血浆BNP水平进行心功能分级，根据心功能分级分别实施心理护理、饮食护理、合理休息及活动、保持大便通畅以及出院前指导等综合护理措施。两组患者于人院后和出院前分别检测血浆脑钠肽（BNP）水平、左室射血分数（LVEF）、左室舒张末期内径（LVEDD）以及计算两组平均住院天数。两组间比较使用t检验和X^2检验。结果出院时干预组血浆BNP水平[（411．8±116．2）pg／mL]明显低于对照组f（522．6±112．4）pg／mL]，两组比较差异有统计学意义（P〈0．05）；干预组LVEF[（49．44±9．82）％]明显高于对照组【（44．73±9．63）％】，两组间比较差异有统计学意义（P〈0．05）；干预组LVEDD[（42．4±6．1）mm]明显小于对照组[（46．7±5．9）mm]，两组比较差异有统计学意义（P〈0．05）；干预组平均住院天数[（15．83±6．62）d]明显少于对照组[（20．78±7．3）d]，两组比较差异有统计学意义（P〈0．05）。结论护理干预用于围生期心肌病患者，可显著改善患者心脏功能，减少住院天数。Objective To explore the effect of nursing intervention on serum brain natriuretic peptide levels in patients with peripartum cardiomyopathy. Methods 60 cases with peripartum cardiomyopathy were randomly divided into inter- vention group （n = 30） and control group （n = 30） in the Cardiovascular Department hospitalization of the People＇s Hospital in Sichuan Province from January 2007 to December 2012. Two groups of patients were given routine treat- ment and care when they were admission. On the based on routine treatment and care, the intervention group were given NYHA classification according to the level of serum BNP and they accepted psychological care, diet care , reasonable rest and activities to keep stool and guidance before leave hospital. Serum BNP, LVEF, LVEDD were evaluated in both groups when the patients were admitted and discharged. Mean hospitalization time was calculated in both groups when the patients discharged. Results The level of BNP in intervention group [（411.8±116.2） pg/mL] were lower than those in control group [（522.6±12.4） pg/mL], the differences were statistically significant （P 〈 0.05）; the LVEF in intervention group [（49.44±9.82）%] were higher than those in control group [（44.73±.63）%], the differences were statistically signif- icant （P 〈 0.05）; the LVEDD in intervention group [（42.4±.1） mm] were lower than those in control group [（46.7±.9） mini, the differences were statistically significant （P 〈 0.05）; the mean hospitalization time in intervention group [（15.83± 6.62） d] were shorter than those in control group [（20.78±7.3） d], the differences were statistically significant （P 〈 0.05）. Conclusion Nursing intervention for perinatal cardiomyopathy patients can greatly improve the heart function and reduce the hospitalization time.

关 键 词：脑利钠肽 围生期心肌病 护理干预 

分 类 号：R473.5[医药卫生—护理学]