葛根异黄酮对运动训练大鼠血液生化指标及抗氧化的影响  

Effects of pueraria isoflavones on blood biochemical and antioxidant indices of swimming training rats

作　　者：陈江林[1] 江丽霞[2] 曾靖[3] 

机构地区：[1]江西省赣州市人民医院肾内科,江西赣州341000 [2]赣南医学院第一附属医院检验科,赣州341000 [3]赣南医学院药学院,赣州341000

出　　处：《中国当代医药》2014年第1期6-8,共3页China Modern Medicine

基　　金：国家自然科学基金(30560173)

摘　　要：目的探讨葛根异黄酮对运动训练大鼠血液生化指标及抗氧化的影响。方法将健康雄性SD大鼠分为安静组、训练组、训练组+不同剂量的葛根异黄酮组。通过游泳运动训练比较各组大鼠血清中血液生化指标(谷草转氨酶、谷丙转氨酶、血糖、全血血红蛋白)及抗氧化能力(超氧化物歧化酶的活性、丙二醛的含量)。结果 100.0、200.0 mg/kg的葛根异黄酮能显著升高运动训练大鼠的血清超氧化物歧化酶活性、血糖、全血血红蛋白含量(P<0.05),并显著降低丙二醛含量和谷草转氨酶活性(P<0.05)。结论葛根异黄酮对运动训练大鼠具有明显的抗氧化作用,可明显改善血液生化指标。Objective To study the effect of pueraria isoflavones on some blood biochemical and antioxidant indices of swimming training rat blood. Methods Healthy male Sprague-Dawley rats were divided into resting groups,training group,and training groups with different dose of pueraria isoflavones.Blood biochemical indices like GOT,GPT,GLU, HHB and antioxidant indices including SOD and MDA were tested. Results 100.0 mg/kg and 200.0 mg/kg pueraria isoflavones could obviously increase the activity of SOD and the content of GLU and HHB （P〈0.05）,meanwhile decrease the content of MDA the activity of GOT （P〈0.05）. Conclusion Pueraria isoflavones on exercise training has obvious an- tioxidant effect in rats and can obviously improve the blood biochemical indexes.

关 键 词：葛根异黄酮 大鼠 运动训练 生化指标 抗氧化 

分 类 号：R332[医药卫生—人体生理学]