妊娠期甲状腺功能亢进患者血清甲状腺功能结果的分析  

Analysis of the serum thyroid function result of pregnancy combined with hyperthyroidism patients

作　　者：张鹏[1] 凌俊辉[1] 吴育平[1] 蔡斯俏[1] 

机构地区：[1]广东省梅州市人民医院,广东梅州514031

出　　处：《中国当代医药》2014年第1期25-27,共3页China Modern Medicine

摘　　要：目的分析妊娠期甲状腺功能亢进患者血清甲状腺功能结果,以探讨其临床价值。方法 43例妊娠期合并甲状腺功能亢进患者为观察组,30例妊娠非甲状腺功能亢进患者为对照组,比较两组不同阶段甲状腺功能结果。结果观察组患者各阶段血清TT3、TT4水平明显高于对照组,差异有统计学意义(P<0.05);妊娠期前1/3阶段观察组患者TRAb阳性率明显低于对照组,差异有统计学意义(P<0.05);妊娠中后1/3阶段两组TRAb阳性率比较差异无统计学意义(P>0.05);妊娠中1/3阶段观察组FT3、FT4水平与对照组比较差异无统计学意义(P>0.05);妊娠后1/3阶段观察组FT3、FT4水平低于对照组,差异有统计学意义(P<0.05)。结论妊娠期甲状腺功能亢进患者血清TT3、TT4水平高表达,妊娠前期TRAb阳性率升高,妊娠后期FT3、FT4水平降低。妊娠期女性应定期进行甲状腺激素检查,尤其是关注TRAb的变化,早发现,早治疗,减少误诊和漏诊等医疗事故的发生。Objective To analyse the serum thyroid function result of pregnancy combined with hyperthyroidism patients in order to study the clinical value.Methods 43 cases of pregnancy combined with hyperthyroidism patients as observation group and 30 cases of pregnancy combined with non-hyperthyroidism patients as control group.Thyroid function results in different stages of two groups were compared.Results The serum TI＇3,TI＇4 levels in different stages of observation group were significantly higher than that of control group,with statistical difference （P〈0.05）.TRAb positive rate in the early 1/3 stage of pregnancy of observation group was lower than that of control group,with statistical differ- ence（P〈0.05）.TRAb positive rate in the middle and later 1/3 stage of pregnancy of two group was compared,with no sta- tistical difference（P〉0.05）.The serum FT3,FI＇4 levels in the middle 1/3 stage of pregnancy of observation group and con- trol group were compared,with no statistical difference （P〉0.05）.The serum gl＇3,gl＇4 levels in later 1/3 stage of observa- tion group were significantly lower than that of control group,with statistical difference （P〈0.05）.Conclusion The serum TY3,TI＇4 levels of pregnancy combined with hyperthyroidism patients has high expression,TRAb positive rate is increased in early pregnancy,the serum FT3,~F4 levels are lower in later pregnancy.Pregnant women should be regularly thyroid hormone examination,especially the change of TRAb,early detection and early treatment,in order to reduce misdiagnosis and miss diagnosis and other medical incidents.

关 键 词：甲状腺功能亢进 妊娠 临床意义 

分 类 号：R581.1[医药卫生—内分泌]