西藏芫根总皂苷减肥作用研究  

The anti-obesity activity of total saponins from Brassica rapa L.

作　　者：杨玲玲[1] 蒋思萍 包善飞[1] 陈志鹃[1] 陈彬 高平[1] 

机构地区：[1]四川大学生命科学学院生物资源与生态环境教育部重点实验室,成都610064 [2]西藏自治区高原生物研究所,拉萨850001

出　　处：《四川大学学报（自然科学版）》2013年第6期1385-1390,共6页Journal of Sichuan University(Natural Science Edition)

基　　金：西藏自治区科技厅重点项目(2005016)

摘　　要：芫根干粉经体积分数70%乙醇提取,石油醚脱脂、水饱和正丁醇萃取,得到芫根总皂苷BTS含量为(6.347±0.627)%.具有降低肥胖大鼠的Lee’s指数,减少肝脏重量及脂肪重量,降低血清TG、TC、MDA的浓度,升高血清HDL-C浓度,提高SOD酶活力的作用.表明芫根总皂苷对高脂饮食诱导的肥胖SD大鼠具有减肥抗氧化作用.The total saponins of Brassica rapa L .（BTS） was extracted with 70% ethanol ,then extracted by petroleum ether and water-saturated butanol successively ,the total saponins were quantified by chro-matometry .The percentage of total saponins in BTS was （6 .347 ± 0 .627）% .The BTS decreased the body weight and liver weight of rats ,lessened Lee’s index and body fat index of fat rats significantly .Ev-ery group of BTS put up obviously effect on lowering the serum TG 、TC、MDA level ,raising HDL-C lev-el and enhancing the activity of SOD .The total saponins of Brassica rapa L .had the activity of anti-o-besity and antioxidation .

关 键 词：芫根 减肥作用 比色法 总皂苷 

分 类 号：Q493.5[生物学—生理学]