栀子清肝汤对Graves病血清促甲状腺素受体抗体的影响  

Effects of Zhiziqinggan decoction on TRAb in patients with graves

作　　者：崔大江[1] 杨渭临[1] 李影娜[1] 田宁艳[1] 傅小平[1] 

机构地区：[1]西安交通大学医学院第二附属医院老年病科,西安710004

出　　处：《临床药物治疗杂志》2013年第6期25-26,51,共3页Clinical Medication Journal

基　　金：一种自拟方剂降低Graves病抗甲状腺药物治疗后复发率的研究(2013K12-09-01)

摘　　要：目的:观察栀子清肝汤对Graves病患者血清促甲状腺素受体抗体(TRAb)的影响。方法:将62例Graves病患者随机分为单纯规范化治疗组(GD单组)和栀子清肝汤加甲巯咪唑组(GD中组),通过长疗程治疗,观察TRAb的阳性率。结果 :治疗后GD中组TRAb阳性7例,阳性率22.58%;GD单组阳性15例,阳性率48.39%,两组有显著性差异(P<0.05)。结论:栀子清肝汤有利于降低Graves病的复发。objective： To observe the effects of Zhiziqinggan decoction on the TRAb in patients with Graves. Methods： A total of 46 patients with Graves were assigned to MMI （GD single group,31 patients ） or Zhiziqinggan decoction combined with MMI （GD middle group,31 patients）. Positive rate of TRAb were analyzed. Results： The positive rate（22.58%,7/31） of TRAb in GD middle group were declined more than in GD single group（positive rate22.58%,15/31）. Conclusion： Zhiziqinggan decoction is benefit for reducing recurrence of Graves.

关 键 词：GRAVES病 栀子清肝汤 血清促甲状腺素受体抗体 

分 类 号：R581.1[医药卫生—内分泌] R289.3[医药卫生—内科学]