2010—2012年晋江市手足口病流行病学特征分析  

Epidemiological characteristics of hand foot and mouth disease in Jinjiang city in 2010-2012

作　　者：杨雅玲[1] 王银雷[1] 林清爽[1] 

机构地区：[1]晋江市疾病预防控制中心防疫科,福建362200

出　　处：《社区医学杂志》2013年第23期61-64,共4页Journal Of Community Medicine

摘　　要：目的对2010-2012年晋江市手足口病（handfootandmouthdisease，HFMD）流行病学特征进行分析，为制订有效防控措施提供依据。方法疫情资料来源于中国疾病预防控制信息系统，病原学资料来源于晋江市疾病预防控制中心实验室数据及泉州市疾病预防控制中心实验结果反馈数据，人口资料来源于晋江市统计年鉴。收集2010年1月1日-2012年12月31日晋江市HFMD病例发病时间、地区、人群分布等资料，运用Excel2007、SPSSl6．0进行统计分析。聚集性病例为《手足口病预防控制指南（2009版）》中对该病的定义。按照《手足口病预防控制指南（2009版）》对HFMD临床诊断病例采集其咽拭子标本，采用实时荧光定量一聚合酶链反应进行病毒核酸检测。结果2010-2012年晋江市共报告HFMD13173例，年发病率分别为230．46／10万、156．21／10万、323．22／10万，发病率先下降后上升。2010年报告重症42例、死亡1例，2011年报告重症28例、死亡1例，2012年报告重症22例、无死亡。重症、死亡病例数逐年下降。5—6月为发病高峰。报告病例数居前三位的乡镇分别是陈埭镇（1653例）、安海镇（1545例）、池店镇（1306例）。2010-2012年各年均1-2岁发病最多，分别占32．74％、34．71％、29．38％；0～3岁共发病10820例，占82．14％。2010-2012年发病男8714例，女4459例，男女比为1．95：1。2010-2012年各年均散居儿童发病最多，分别占76．49％、80．47％、72．95％。92例重症病例中肠道病毒71型（enterovirus，EV71）感染91例。2010-2012年共处理HFMD聚集性疫情66起，单纯家庭聚集性疫情占50．00％。结论2010-2012年晋江市HFMD疫情呈上升趋势，病原学检测结果显示病毒以EV71为主，疫情具有明显人群、地区和季节特征。Objective To analyze the epidemiological characteristics of hand foot and mouth disease（HFMD） in Jinjiang City in 2010-2012,and to provide scientific evidence for formulating the more efficient prevention and control tactics.Methods The data of HFMD were from China Information System for Disease Prexention and Control were analyzed;the etiological materials were collected from the data of our central lab and the feedback data of the experimental results from Quanzhou Center for Disease Prevention and Control;while the demographic data were from Jinjiang Statistical Yearbook.Information about the onset time,area and population distribution of HFMD in Jinjiang city from January lst,2010 to December 31st,2012 were collected and were ana- lyzed statistically with Excel2007 and SPSS16.0.Clustering cases were determined according to the definition of such disease giv- en in Guidelines for Prevention and Control of Hand foot and Mouth Disease （2009）.Throat swab samples of HFMD cases diag- nosed in clinic were collected according to the guidelines and nucleic acid testing was conducted through real-time fluorescent quantitative polymerase chain reaction（FQ-PCR）.Results A total of 13 173 HFMD cases were reported in Jinjaing city in 2010-2012.The average incidence rate of HFMD of each year was 230.46/105,156.21/105,323.22/105.The number of severe and death cases declined gradually in 2010-2012.The peak incidence occurred during the period from May to June.The top three towns with large number of cases are Chendai town （1 653 cases）,Anhai town （1 545 cases）,Chidian town（1 306 cases）.Of 13 173 HFMD cases,the children of 0-3 years old accounted for 82.14%（10 820/13 173）,The number of male cases （8 714） was larger than that of the female（4 459）,the ratio was 1.95：l.Scattered children accounted for,respectively,76.49%,80.47%,72.95% in 2010-2012.Among the 92 severe cases,91 cases were caused by enterovirus 71 （EV71）.Of 66 cases of epidemic aggregation of I-IFMD reported in 2010-2012,simp

关 键 词：手足口病 流行病学特征 传染病 

分 类 号：R195.4[医药卫生—卫生统计学]