万州区儿童维生素D营养状况及其与身高发育的关系研究  

Vitamin D nutritional status and its relationship with height developmental research of children in Wanzhou district

作　　者：李波[1] 谭祥权[2] 罗佳美[3] 胡海艳[1] 宋敏[1] 

机构地区：[1]重庆三峡中心医院儿童分院检验科,404000 [2]重庆三峡中心医院儿童分院儿内科,404000 [3]重庆三峡中心医院儿童分院儿保科,404000

出　　处：《重庆医学》2013年第33期4070-4072,共3页Chongqing medicine

摘　　要：目的分析重庆万州区儿童维生素D营养状况及其与身高发育的关系。方法选取重庆万州区2 727名儿童,采用电化学发光免疫分析方法(ECLLA)检测血清25-羟基维生素D[25(OH)D]浓度,同时采集儿童年龄、性别、身高、父母身高等指标,分析25(OH)D与其相关性。结果万州区儿童血清25(OH)D浓度在不同年龄组间比较差异有统计学意义(P<0.01),同一年龄不同性别间5个月、6个月、4岁、5岁组差异有统计学意义。万州区儿童6岁后身高逐渐落后于全国平均水平。调整年龄、性别、父母身高、测量季节等影响因素后,血清25(OH)D浓度与身高呈正相关(r=0.462 5,P<0.01)。结论 25(OH)D水平与儿童身高发育间关系密切,而万州区儿童25(OH)D营养状况普遍较差,这应引起重视。Objective To analyze Vitamin D nutritional status of children and their height growth relationship in Wanzhou dis-trict of Chongqing .Methods Electrochemiluminescence immunoassay method was used to detect serum 25 hydroxyvitamin D [25 （OH） D]concentrations in 2 727 Children from Wanzhou district of Chongqing ,analyzing the correlation of Vitamin D and children age ,gender ,height ,parental height and other factors .Results There was significant difference in serum level of 25（OH） D among different age groups（P〈0 .01） ,there was significant difference between boys and girls among the same age groups of 5 months ,6 months ,4 years old ,5 years old .Children′s height consistented with the national average 4 -6 years ago in Wanzhou District ,but Since then ,gradually felled behind .After adjustment for age ,sex ,parental height ,measured seasonal and other factors ,serum 25 （OH） D concentration was positively correlated with height （r=0 .462 5 ,P〈0 .01） .Conclusion 25（OH）D levels were closely re-lated with the development of children′s height .Thus ,children generally poor 25（OH）D nutritional status in Wanzhou district should arouse the attention of parents and clinicians .

关 键 词：儿童 身高 维生素D 25-羟维生素D 

分 类 号：R723[医药卫生—儿科]