散发性戊型肝炎流行病学和临床特征分析  

Epidemiologic and clinical features of patients with sporadic viral hepatitis E

作　　者：胡晓武[1] 

机构地区：[1]安徽省淮南市第一人民医院感染病科,232007

出　　处：《实用肝脏病杂志》2013年第6期520-522,共3页Journal of Practical Hepatology

摘　　要：目的：了解近年散发性戊型肝炎的发病特点。方法回顾性分析2009年1月～2012年12月收治的305例戊型肝炎患者的流行病学和临床资料。结果本研究纳入男性221例（72.7%），女性84例（27.3%），平均年龄57.8岁；在2009年、2010年、2011年和2012年，40～59岁年龄组发病率分别为33.3%、48.7%、46.3%和50.9%，除2009年外，均明显高于其他年龄组（P＆lt;0.05）；大于60岁年龄组患者血清胆红素峰值为（254.21＆#177;103.9）μmol/L，明显高于其他年龄组患者（P＆lt;0.05）。结论散发性戊型肝炎呈发病率增加和年轻化趋势，需要加强监管和治疗。Objective To explore the epidemiologic and clinical characteristics of patients with sporadic hepatitis E in recent years. Methods A total of 305 patients with hepatitis E from Jan. 2009 to Dec. 2012 in our hospital were included. The epidemiologic and clinical features of patients were analyzed retrospectively. Re-sults There were 221 male （72.7%）and 84 female （27.3%）patients were included in this study,with an average age of 57.8;The incidence in patients aged from 40 to 59-yr-old in 2009,2010,2011 and 2012 were 33.3%, 48.7%,46.3% and 50.9%,all but 2009 were higher than those in patients younger than 40 or older than 60（P＆lt;0.05）;The serum bilirubin levels at peak in patients older than 60 were 254.21＆#177;103.9μmol/L,much higher than those in patients younger than 60（P＆lt;0.05）. Conclusions The incidence of sporadic viral hepatitis E is increasing in recent years with a trend of younger age of the patients. More attention should be put into the surveillance and treatment of this disease.

关 键 词：戊型肝炎 流行病学 临床特征 

分 类 号：R512.63[医药卫生—内科学]