Preparative separation and purification of deoxyschizandrin from Schisandrae Sphenantherae Fructus by high-speed counter-current chromatography  

作　　者：Xin-Ying Li Mei Yang Jie-Yun Huang Xiao-Xue Yua Min-Qian Zhao Zhi-Kun Liang Zhi-Sheng Xie Xin-Jun Xu 

机构地区：[1]School of Pharmaceutical Sciences,Sun Yat-Sen University [2]Guangdong Technology Research Center for Advanced Chinese Medicine

出　　处：《Journal of Pharmaceutical Analysis》2013年第6期429-433,共5页药物分析学报（英文版）

基　　金：supported by the International Scientific and Technological Cooperation Program of China(No.2009DFA31230);the Industry-University-Research Cooperation Program from Science and Technology Department of Guangdong Province(No.2010B090400533)

摘　　要：A high-speed counter-current chromatography （HSCCC） method was successfully developed for the preparative separation and purification of deoxyschizandrin from Schisandrae Sphenantherae Fructus in one step. The purity of deoxyschizandrin was 98.5%, and the structure was identified by MS, UV and NMR. This method was simple, fast, convenient and appropriate to prepare pure compound as reference substances for related research on Schisandrae Sphenantherae Fmctus.A high-speed counter-current chromatography （HSCCC） method was successfully developed for the preparative separation and purification of deoxyschizandrin from Schisandrae Sphenantherae Fructus in one step. The purity of deoxyschizandrin was 98.5%, and the structure was identified by MS, UV and NMR. This method was simple, fast, convenient and appropriate to prepare pure compound as reference substances for related research on Schisandrae Sphenantherae Fmctus.

关 键 词：Schisandrae Sphe-nantherae Fructus High-speed counter-cur-rent chromatography（HSCCC） DEOXYSCHIZANDRIN 

分 类 号：R284[医药卫生—中药学]