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作 者:张文豪[1] 陈敏洁[1] 柴盈[1] 张伟杰[1]
机构地区:[1]上海交通大学附属口腔医学院颌面外科,上海200010
出 处:《口腔医学研究》2013年第12期1121-1124,共4页Journal of Oral Science Research
基 金:国家自然科学基金青年基金(编号:81100824);上海市教育委员会创新科研基金(编号:12YZ044)
摘 要:目的:通过电生理监测下选择性舌咽神经切断术(selective rhizotomy of glossopharyngeal nerve,SRGN)治疗舌咽神经痛,以提高有效率及减少并发症的发生。方法:2009年12月~2012年5月对8例舌咽神经痛患者进行舌咽神经切断术,均采用枕下乙状窦后入路,术中首先刺激舌咽神经,分别在软腭和环甲肌得到一个波形,记录波幅Aa和Ab,其次,刺激最下方的迷走神经,即最远离舌咽神经的迷走神经根丝,在软腭和环甲肌各得到一个波形,记录波幅Am和An。再次,刺激最邻近舌咽神经下方的混合根丝,在软腭和环甲肌分别得到一个波形,记录波幅Ax和Ar若A,/An〈50%,则予以切断,若A,/A.〉50%,则予以保留。结果:A.平均为(54±8.3)uV(40~80uV),A.平均为(138±18.9)uV(120~160uV),Am平均为(192±8.1)肛V(180~200uV),Ab平均为(12±9.5)肛V(10~30uV),Ay平均为(22±5.5)肛V(20~30弘V),An平均为(36±7.2)弘V(30~50uV)。8例患者经3月~3年的随访,有效率为100%,并发症发生率0%。7例(87.5%)疼痛完全缓解(优),其中6例术后即刻缓解;1例术后1月完全缓解。1例(12.5%)中度缓解,卡马西平600mg/d可控制(良)。7例疗效为”优”的患者未发生声音嘶哑、吞咽困难及饮水呛咳等并发症。1例疗效为”良”的患者却有呛咳症状,术后2月缓解。结论:术中刺激舌咽、迷走神经及其交通支,在软腭及环甲肌记录的监测方法可获得一个量化标准,提高SRGN有效率、减少并发症发生率。Objective: To evaluate the selective rhizotomy of glossopharyngeal nerve (SRGN) under electrophysio logical monitoring in treatment of glossopharyngeal neuralgia(GPN). Methods: From December 2009 to May 2012, SRGN was carried out on 8 patients with GPN. Suboccipital sigmoid sinus posterior access was employed for all pa tients. 3 groups of the amplitudes were recorded: Aa and Ab - the glossopharyngeal nerve was stimulated; Am and An - the part of the vagus nerve, which was most away from the glossopharyngeal nerve, was stimulated; Ax and Ay - the mixed nerve root which Was close to the glossopharyngeal nerve was stimuiated. The glossopharyn geal nerve was cut off. The vagus nerve was preserved. If Ay/An 〈50%, the mixed nerve root should be cut off, and if Ay/An 〉 50%, then the mixed nerve root should be retained. Results: As the representation of glossopha ryngeal nerve, the average of Aa, Ax, Am were 54uv(40uv~80uv), 138uv(120uv~160uv) ,192uv(180uv~200uv) respectively. As the representation of vagus nerve, the average of Ab, Ay, An were 12uv(10uv~30uv) ,22uv(20uv 30uv), 36uv(30uv~ 50uv) respectively. 7 patients (87.5 % ) obtained complete pain relief (excellent). One case (12.5 %) obtained moderate relief(good), and can be controlled with Carbamazepine at a dosage of 600mg/d. The bucking was occurred in this patient, and relieved in two months after operation. Conclusion: SRGN under electro physiological monitoring can improve the efficiency of pain relief and reduce the incidence of complications.
关 键 词:舌咽神经痛 电生理监测 选择性舌咽神经切断术 迷走神经
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