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作 者:郝小芳[1,2] 项尚林[1] 石磊 刘超[1] 吴新上[3]
机构地区:[1]南京工业大学材料科学与工程学院,江苏南京210009 [2]江苏省医疗器械检验所,江苏南京210012 [3]江苏中金玛泰医药包装有限公司,江苏连云港222047
出 处:《中国胶粘剂》2013年第12期27-30,共4页China Adhesives
摘 要:以IPDI(异佛尔酮二异氰酸酯)、磺化聚酯多元醇和DMPA(二羟甲基丙酸)等为主要原料,制备了医药包装用WPU(水性聚氨酯)胶粘剂;然后将其涂敷在铝箔带上,制备相应的铝箔带胶膜,并对其阻隔性能、热封强度、易氧化物含量和有机溶剂残留量等进行了测定。研究结果表明:当R=n(IPDI中-NCO)/n(磺化聚酯多元醇中-OH)=3.5时,铝箔带胶膜的阻隔性能、热封强度(11.9 N/15 mm)、易氧化物含量(≤0.5 mL)和有机溶剂残留量等均符合医药包装材料的使用要求。With IPDI (isophorone diisocyanate), sulfonated polyester polyol and DMPA (dihydromethyl propionic acid) as main raw materials, a WPU (waterborne polyurethane) adhesive for packing drugs was prepared. Then, the WPU adhesive was coated on aluminum foil, so a corresponding aluminum foil tape,which some properties such as barrier property ,heat-seal strength, easy oxidizable substance contents and residual organic solvent contents were tested,was prepared. The research results showed that the barrier property,heat-seal strength (11.9 N/15 mm), easy oxidizable substance contents(not more than 0.5 mL) and residual organic solvent contents could all meet application requirements of material for packing drugs when R value or molar ratio of n(-NCO in IPDI)/n(-OH in sulfonated polyester polyol) was 3.5.
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