二(2-乙基己基)磷酸钠对氨基葡萄糖盐酸盐的离子交换萃取与反萃  

Ion-exchange Extraction and Back Extraction of Glucosamine Hydrochloride with Sodium Di-(2-ethylhexyl) Phosphate

作　　者：黄捷[1] 罗能镇 沈剑[1] 相咸高 钱超[1] 徐义明 周俊超 何潮洪[1] 

机构地区：[1]化学工程联合国家重点实验室浙江大学、浙江大学化学工程与生物工程学系,浙江杭州310027 [2]中建安装工程有限公司,江苏南京210046

出　　处：《高校化学工程学报》2013年第6期960-966,共7页Journal of Chemical Engineering of Chinese Universities

基　　金：浙江省自然科学基金杰出青年团队项目(R4090358);浙江省重点科技创新团队(2009R50002,2010R50017)

摘　　要：水解法制备氨基葡萄糖盐酸盐的产品初浓度只有3%(wt)左右,需采用重结晶等传统工艺提纯,十分耗能。若能利用萃取-反萃工艺进行浓缩或提纯,在节能降耗方面将有重要意义。今研究了离子交换萃取法在氨基葡萄糖盐酸盐提纯上的应用。选用工业级二(2-乙基己基)磷酸制备钠盐作为萃取剂,以工业无味煤油作为稀释剂,研究了萃取剂初始浓度、NaCl浓度、温度和水相pH等因素对分配系数的影响,结果表明,分配系数随氯化钠初始浓度的增加而降低,随初始萃取剂浓度和温度的增加而升高,随平衡pH的降低而降低。此外,利用pH摆动效应,用浓盐酸实现了离子交换萃取的反萃过程,对比了有机相络合物浓度对反萃分配系数、反萃率等参数的影响,并实现了萃取剂的皂化再生。The initial concentration of glucosamine hydrochloride product prepared via acidic hydrolysis is only approximately 3%（wt）. The conventional purification method is recrystallization, which requires high-energy consumption. Therefore, developing an energy-efficient process is of great significance. In this paper, an ion-exchange extraction process was investigated by using sodium di-（2-ethylhexyl） phosphate （D2EHPNa） of industrial grade as the extractant and kerosene of industrial grade as the diluent. The effects of the initial concentrations of D2EHPNa and NaC1, temperature and pH of the aqueous solution on distribution coefficient were studied. The results indicate that the distribution coefficient decreases with the increase of initial concentration of NaC1, increases with the increase of the initial concentration of D2EHPNa and temperature, and decreases with decrease of pH. In addition, the back extraction by concentrated hydrochloric acid was investigated according to the pH swing effect, and the extractant was regenerated after back extraction.

关 键 词：氨基葡萄糖盐酸盐 二(2-乙基己基)磷酸钠 离子交换萃取 分配系数 反萃 pH摆动效应 萃取剂再生 

分 类 号：TQ028.8[化学工程] TQ028.33