重症监护室耐甲氧西林金黄色葡萄球菌主动筛查检出率分析  

Active screen on isolation rate of methicillin-resistant Staphylococcusau reusin intensive care unit patients

作　　者：谢懿[1] 黄淑芬[1] 曾娟[1] 李忠新[1] 

机构地区：[1]深圳市中医院,广东深圳518033

出　　处：《中国感染控制杂志》2013年第6期418-420,共3页Chinese Journal of Infection Control

基　　金：深圳市科技计划项目(201103394)

摘　　要：目的对某院重症监护室(ICU)住院患者开展快速准确的耐甲氧西林金黄色葡萄球菌(MRSA)主动筛查,为临床推广MRSA主动筛查和制定更有效的多重耐药菌感染控制措施提供依据。方法将2011年11月1日—2012年4月30日入住该院ICU的患者设为对照组(79例,采用常规细菌培养方法对疑似感染患者进行MRSA检测),2012年6月1日—11月30日入住该院ICU的患者设为干预组(86例,采用快速可靠的MRSA产色培养基对该组患者进行MRSA主动筛查),对比分析两组的MRSA检出率。结果干预组和对照组患者在年龄、疾病分类评分、置管率方面比较,差异均无统计学意义(P>0.05);对照组的平均住院时间为(20.77±7.27)d,显著长于干预组的(18.13±6.90)d(t=2.39,P=0.02)。干预组与对照组患者在入ICU时MRSA检出率分别为3.80%(3/79)和1.16%(1/86),出ICU时MRSA检出率分别为5.06%(4/79)和5.81%(5/86),差异均无统计学意义(P>0.05)。结论选用MRSA产色培养基开展主动筛查,可以为及时实施接触隔离预防措施提供循证依据,更有利于接触预防措施的落实。ObjectiveTo perform rapid and accurate active screen on methicillinresistant Staphylococcus aureus （MRSA） in patients in an intensive care unit（ICU）, and provide evidence for making effective measures of controlling multidrugresistant bacterial infection.MethodsPatients who were hospitalized between November 1,2011 and April 30,2012 were in control group （79 cases, patients suspected with MRSA infection were performed MRSA detection with routine bacterial culture method）, and patients who were hospitalized between June 1,2012 and November 30,2012 were in intervention group （86 cases, patients were performed active screen with MRSA chromogenic medium）, MRSA detection rate between two groups was compared.ResultsThe differences in age,score of disease classification, catheterization rate between two groups were not significantly different （P〉0.05）; the average length of hospital stay in control group was significantly longer than that of intervention group （［20.77±7.27］d vs［18.13±6.90］d, t=2.39，P=0.02）. The detection rate of MRSA at admission to ICU in intervention group and control group was 3.80%（3/79） and 1.16%（1/86）respectively（P＞0.05）, at discharge was 5.06%（4/79）and 5.81%（5/86）respectively（P＞0.05）.ConclusionActive screen on MRSA with chromogenic medium can provide evidence for timely contact isolation，and is more effective to enforce contact precaution measures.

关 键 词：重症监护室 金黄色葡萄球菌 耐甲氧西林金黄色葡萄球菌 主动筛查 医院感染 感染控制 

分 类 号：R181.32[医药卫生—流行病学]