表达谱芯片技术在动物胚胎发育研究中的应用进展  

The Research Progress of Expression Profile Chip Technology Application in the Animal Embryonic Development

作　　者：吴伟伟[1] 宫平[1] 哈尼克孜[1] 石晓雷[1] 于丽娟[1] 徐新明[1] 田月珍[1] 田可川[1] 

机构地区：[1]新疆畜牧科学院畜牧研究所,新疆乌鲁木齐830000

出　　处：《草食家畜》2013年第6期1-5,12,共6页Grass-Feeding Livestock

基　　金：自治区公益性院所基金项目;国家农业杰出人才及创新团队建设项目;国家绒毛用羊产业技术体系(CARS-40)

摘　　要：基因表达谱芯片在基因芯片中应用最广泛,具有灵敏、高效、平行化、高通量等优点,可检测胚胎发育过程中成千上万个基因的表达情况,绘制基因表达图谱,筛选特异性表达基因,从而揭示胚胎发育过程在基因水平上的本质。近年,利用表达谱芯片技术检测胚胎发育不同时期中miRNA的表达情况取得一定进展,这对全面研究胚胎基因组激活、胚胎发育阻滞等问题具有重要意义,本文对此进行综述。Gene expression profile chip, is the most widely used in gene chip, has advantages of sensitive, high efficient , parallel and the high throughput, Can detect the expression of thousands of genes in the process of embryonic development, draw gene expression mapping, screen specificity expressed genes, and reveals the essence of the embryonic development process at the gene level. In recent years, the use of expression profile chip technology has a certain progress of detect the expression of microRNA in the embryonic development, it has great significance in research of embryonic genome activation and embryo developmental block. This paper summarized.

关 键 词：表达谱芯片 动物 胚胎发育 

分 类 号：S818.9[农业科学—畜牧学]