颜面播散性粟粒性狼疮21例临床分析  

Clinical Analysis of 21 Cases with Lupus Miliaris Disseminatus Faciei

作　　者：瓦庆彪[1] 陈前明[1] 李烜[1] 蔡琦[1] 吴波[1] 路永红[1] 谢立夏[1] 

机构地区：[1]成都市第二人民医院皮肤科,四川成都610017

出　　处：《中国皮肤性病学杂志》2014年第1期43-45,共3页The Chinese Journal of Dermatovenereology

摘　　要：目的探讨颜面播散性粟粒性狼疮的临床及病理特点,减少误诊,及早确诊,并依据痛期给予恰当的治疗。方法回顾性分析2008年1月-2011年10月本科诊治的21例颜面部播散性粟粒性狼疮患者的临床资料。结果本病好发于青壮年,皮疹多累及眼周,表现为先滑的红褐色丘疹或萎缩性瘢痕;组织病理主要为上皮样细胞肉芽肿,典型病例可见干酪祥坏死;可依据病程选择相应治疗。结论对病程长、发展缓慢的眼周及面部多发的丘疹,应借助组织病理学排除颜面部播散性粟粒性狼疮,早期诊断可加强抗炎治疗,以避免瘢痕形成。Objective To reveal the clinical and pathological features of Lupus miliaris disseminatus faciei（LMDF） in order to reduce misdiagnosis, to make earlier diagnosis, and to provide appropriate treatment. Methods The clinical data of 21 patients with LMDF from 2008 - 2011 were retrospectively analyzed. Results Larger portion of LMDF subjects were young patients. Smooth, red-brown papules or atrophic scars were often seen around eyes. Histological changes included epithelioid cell granulomas and caseous necrosis in typical cases. Treatment options for LMDF were based on it＇s course. Conclusion Histopathological examination should be done to exclude LMDF if patients experience slowly developed multiple papules on the face. Early diagnosis and anti-inflammatory treatment can reduce the risk of scar formation.

关 键 词：颜面播散性粟粒性狼疮 临床分析 

分 类 号：R593.24[医药卫生—内科学]