Glucose biosensor based on new carbon nanotube–gold–titania nano-composites modifed glassy carbon electrode  

作　　者：Yue-Li Wu Qi-Wei Li Xiao-Lu Zhang Xiao Chen Xue-Mei Wang 

机构地区：[1]School of Chemistry and Chemical Engineering,Southeast University [2]State Key Lab of Bioelectronics,Southeast University

出　　处：《Chinese Chemical Letters》2013年第12期1087-1090,共4页中国化学快报（英文版）

基　　金：support from National Key Basic Research Program (No. 2010CB732404);National Natural Science Foundation of China (No. 21175020);Qinglan Project Sci-Tech Innovation Team of Jiangsu Province;Suzhou Science & Technology Major Project (No. ZXY2012028)

摘　　要：In this paper, a novel biosensor was prepared by immobilizing glucose oxidase （GOx） on carbon nanotube-gold-titania nanocomposites （CNT/Au/TiO2） modified glassy carbon electrode （GCE）. SEM was initially used to investigate the surface morphology of CNT/Au/TiO2 nanocomposites modified GCE, indicating the formation of the nano-porous structure which could readily facilitate the attachment of GOx on the electrode surface. Cyclic voltammogram （CV） and electrochemical impedance spectrum （EIS） were further utilized to explore relevant electrochemical activity on CNT]Au/TiO2 nanocomposites modified GCE. The observations demonstrated that the immobilized GOx could efficiently execute its bioelectrocatalytic activity for the oxidation of glucose. The biosensor exhibited a wider linearity range from 0.1 mmol L-1 to 8 mmol L^-1 glucose with a detection limit of 0.077 mmol L^- 1.In this paper, a novel biosensor was prepared by immobilizing glucose oxidase （GOx） on carbon nanotube-gold-titania nanocomposites （CNT/Au/TiO2） modified glassy carbon electrode （GCE）. SEM was initially used to investigate the surface morphology of CNT/Au/TiO2 nanocomposites modified GCE, indicating the formation of the nano-porous structure which could readily facilitate the attachment of GOx on the electrode surface. Cyclic voltammogram （CV） and electrochemical impedance spectrum （EIS） were further utilized to explore relevant electrochemical activity on CNT]Au/TiO2 nanocomposites modified GCE. The observations demonstrated that the immobilized GOx could efficiently execute its bioelectrocatalytic activity for the oxidation of glucose. The biosensor exhibited a wider linearity range from 0.1 mmol L-1 to 8 mmol L^-1 glucose with a detection limit of 0.077 mmol L^- 1.

关 键 词：Biosensor Glucose oxidase CNT/Au/TiO2 

分 类 号：O646.54[理学—物理化学]