An effcient,rapid and facile procedure for conversion of aldoximes to nitriles using triphenylphosphine and N-halo sulfonamides  

作　　者：Ramin Ghorbani-Vaghei Lotf Shiri Arash Ghorbani-Choghamarani 

机构地区：[1]Department of Organic Chemistry,Faculty of Chemistry,Bu-Ali Sina University [2]Department of Chemistry,Faculty of Sciences,Ilam University

出　　处：《Chinese Chemical Letters》2013年第12期1123-1126,共4页中国化学快报（英文版）

基　　金：Bu-Ali Sina University, Center of Excellence and Development of Chemical Methods (CEDCM) for fnancial support

摘　　要：N,N,N＇,N＇-Tetrabromobenzene-1,3-disulfonamide （TBBDA）/triphenylphosphine and N,N,N＇,N＇-tetra- chlorobenzene-1,3-disulfonamide （TCBDA）/triphenylphosphine have been introduced as highly efficient systems for the versatile conversion of aldoxime derivatives into nitriles. The process reported here is operationally simple and reactions have been mildly performed in dichloromethane at room temperature.N,N,N＇,N＇-Tetrabromobenzene-1,3-disulfonamide （TBBDA）/triphenylphosphine and N,N,N＇,N＇-tetra- chlorobenzene-1,3-disulfonamide （TCBDA）/triphenylphosphine have been introduced as highly efficient systems for the versatile conversion of aldoxime derivatives into nitriles. The process reported here is operationally simple and reactions have been mildly performed in dichloromethane at room temperature.

关 键 词：Aldoxime Nitrile N N N＇ N＇-Tetrabromobenzene-1 3- disulfonamide N N N＇ N＇-Tetrachlorobenzene-1 3- disulfonamide Triphenylphosphine （PPh3） 

分 类 号：TQ463.6[化学工程—制药化工]