N-苄基-2,4-二硝基咪唑的合成及其亲核取代反应  

Synthesis of N-Benzyl-2,4-dinitroimidazole and Its Nucleophilic Substitution Reactions

作　　者：李明梅[1] 

机构地区：[1]盐城卫生职业技术学院,江苏盐城224005

出　　处：《化学世界》2013年第12期745-746,765,共3页Chemical World

摘　　要：以2,4-二硝基咪唑为原料,经N-苄基保护合成出N-苄基-2,4-二硝基咪唑,并研究了其亲核取代反应,结果表明-N3、-F、-OCH3可以高收率的取代2位硝基,产物经核磁、质谱、元素分析进行了表征。N-Benzyl-2,4-dinitroimidazole was obtained using 2,4-dinitroimidazole as raw material, and its nucleophilic substitution reactions were described. The results showed that-N3, -F, -OCH3 can substitute the 2- nitro group in high yield. All the products were confirmed by H NMR, MS and elemental analysis.

关 键 词：合成 N-苄基-2  4-二硝基咪唑 亲核取代 

分 类 号：O621.3[理学—有机化学]