生活方式干预对空腹血糖受损人群的影响  

Effects of Lifestyle Intervention on Patients with Impaired Fasting Glucose

作　　者：戴霞[1] 罗佐杰[1] 陈青云[1] 周爱民[1] 秦映芬[1] 游越西[1] 何燕玲[1] 

机构地区：[1]广西医科大学第一附属医院,南宁市530021

出　　处：《广西医学》2013年第12期1591-1594,共4页Guangxi Medical Journal

基　　金：广西自然科学基金(0832131)

摘　　要：目的探索强化生活方式干预对空腹血糖受损(IFG)人群的影响。方法采取前瞻性研究方法,随机抽取南宁市、柳州市4个社区IFG患者300例,采用抓阄法随机分成4组:对照组(A组)、单纯运动治疗组(B1组)、饮食控制加运动组(B2组)、饮食控制加标准量化运动方案组(B3组)。监测各组干预前及干预1年、2年后FBG、2hPG、HbA1c、TC、TG、HDL、LDL、体重、腰臀比,采用抑郁自评量表(SDS)评价干预前后抑郁情况。结果干预1年、2年后相对于A组、B1组、B2组,B3组IFG患者TC、TG、HDL、LDL、体重、腰臀比、HbA1c、FBG、2hPG指标改善效果更明显(P<0.05);(2)B3组IFG转归率高于另外3组(P<0.05);B3组抑郁检出率均低于其他3组,SDS得分均低于其他3组(P<0.05)。结论加强饮食控制+运动处方的生活干预方式可有效改善IFG患者的血糖、血脂,提高空腹血糖转归率。Objective To explore the effects of lifestyle intervention including exercise training and dietary therapy on patients with impaired fasting glucose（IFG）. Methods We adopted prospective study method and selected 400 IFG cases from four communities in Nanning and Liuzhou. The patients were divided randomly into four groups： control group（group A） ,exercise training group（group B1） ,ordinary dietary therapy and exercise training group（group B2） ,dietary therapy and exercise prescription training group （ group B3 ）. FBG,2hPG, HbA1 c, TG, TC, HDL, LDL, body weight and waist to hip ratio were monitored in each group as well as SDS was adopted to evaluate the patients＇ depression state before and after intervention. Results ① Compared with group A, B1,B2,TG, TC,HDL, LDL, body weight,waist-to-hip ratio, HbAlc,FPG,2hPG of IFG patients in group B3 improved significantly after 1- or 2-year intervention （P 〈 0.05 ）. ② The recovery rate of blood glucose of IFG patients in group B3 was significantly higher than those in the other groups （ P 〈 0.05 ）. ③ The positive rate of depression and SDS score of patients in group B3 were significantly lower than those in the other groups （P 〈 0. 05 ）. Conclusion The combined application of exercise prescription training and strengthened dietary therapy in lifestyle intervention can improve blood glucose,blood lipids of IFG patients effectively, which might elevate the recovery rate of FBG.

关 键 词：生活方式 FBG受损 干预性研究 

分 类 号：R587.3[医药卫生—内分泌]