红外光谱法与化学法对尿路结石主要成分分析比较  

Comparision between Infrared Spectroscopy and chemical method in analyzing components of lithangiuria

作　　者：韩琛璐 冯凤玉 陈慧[1] 佃林萍 黄思琪[1] 林思美 潘筱媛[1] 朱寒亮[2] 吴文起[2] 

机构地区：[1]广州医科大学第一临床学院,510120 [2]广州医科大学附属第一医院泌尿外科/广东省泌尿外科重点实验室,510230

出　　处：《检验医学与临床》2013年第24期3258-3259,3262,共3页Laboratory Medicine and Clinic

基　　金：卫生部行业科研专项资助项目(子课题)(201002010)

摘　　要：目的通过红外光谱分析法及化学法对尿路结石进行成分分析,比较二者在尿路结石诊断及预防中的临床价值。方法分别应红外光谱法和化学法对903例尿路结石进行成分分析,并对分析结果进行总结。结果红外光谱分析法测得的结石晶体成分类型明显多于化学分析法,二者检测为同一种主要成分的比例为76.30%,其中草酸钙结石检出率最高。与红外光谱分析法比较,化学法对草酸钙的检测灵敏度为98.34%(653/664),差异无统计学意义(P>0.05),特异度为22.59%(54/239),差异有统计学意义(P<0.01)。结论红外光谱法及化学法对尿路结石成分分析均具有临床意义,但前者准确性更高,应根据实际情况选择结石分析方法。Objective To analyse the main component of lithangiuria by infrared spectroscopy and chemical method ,and to compare the clinical value of these two methods in the diagnosis and prevention lithangiuria . Methods Themain component of lithangiurias from 903 cases were determined by infrared spectroscopy and chemical method respectively ,and then summarized the result combining with clinical datas .Results Types of stone crystal components detected by infrared spectroscopy were significant more than types detected by the chemical method ,and the proportion of consistency result from these two methods was 76 .30% ,with the highest detection rate of calcium oxalate stones .Compared with infrared spectroscopy ,the detection sensitivity of calcium oxalate stones by chemical method was 98 .34% （653/664） ,there was no difference between the two methods （P〉0 .05）;And the specificity was 22 .59% （54/239） ,there was significant difference between them （P〈0 .01） .Conclusion Both of infrared spec-troscopy and chemical method have clinical value to analysis lithangiuria ,and the former has higher accuracy .The stone analysis methods should be chose according to the actual situation of the hospital .

关 键 词：尿路结石 红外光谱法 化学法 分析比较 

分 类 号：R378.41[医药卫生—病原生物学]