水蛭素联合阿霉素对人卵巢癌细胞株耐药性的实验观察  

Experimental Observation of Hirudin combined with Adriamycin on Resistance of Human Ovarian Cancer Cell Line

作　　者：黄晓丽[1] 蔡捷[1] 苏承武[1] 潘复泽[1] 廖翠芳 李丽梅[1] 

机构地区：[1]广西医科大学,广西南宁530021

出　　处：《蛇志》2013年第4期365-366,共2页Journal of Snake

基　　金：广西医科大学七年制临床科研课题(编号:02607211042);广西教育厅研究生教育和改革创新课题(编号:09110025)

摘　　要：目的探讨水蛭素联合阿霉素对人卵巢癌细胞生长的影响。方法通过细胞培养后绘制生长曲线,了解联合用药对抑制癌细胞增殖及诱导凋亡的作用。结果水蛭素联合阿霉素具有杀伤人卵巢癌细胞的效果。结论水蛭素有可能作为临床抗癌和抑癌治疗的潜在辅助用药。Objective To investigate the effect of hirudin combined with adriamycin on the growth of human ovar-ian cancer cells. Methods Draw cell growth curve through the cell culture.Investigate the growth inhibition and apoptosis induction of combined medication on cancer cells. Results Hirudin combined with adriamycin has the effect of killing human ovarian cancer cells. Conclusion Hirudin could be used as potential adjuvant anticancer in clinical cancer treatment.

关 键 词：水蛭素 阿霉素 联合用药 人卵巢癌细胞株 

分 类 号：S966.9[农业科学—水产养殖]