植物中一组杂环取代的丙氨酸衍生物研究进展  

Study on the Group of Heterocyclic β-substituted α-alanines in Plants

作　　者：董晓宁[1] 王小芳[1] 杨玲娟[1] 袁毅君[1] 赵菲佚[1] 焦成瑾[1] 

机构地区：[1]天水师范学院生命科学与化学学院,天水741001

出　　处：《天然产物研究与开发》2013年第12期1759-1768,共10页Natural Product Research and Development

基　　金：国家自然科学基金项目(31160060;31260568)

摘　　要：本文对含羞草氨酸、使君子氨酸、黧豆素、西瓜子氨酸等9种丙氨酸衍生的非蛋白氨基酸的种属分布、生物合成及生理活性研究作综述,并对进一步研究作简单讨论。The amino acids characterised as the heterecyclic β-substituted α-alanines are an important part of non-protein amino acids in plants, some of which were found to be synthesized by cysteine synthase. In the reactions, one of the hy- drogen atoms of β carbon in alanine is replaced with a heteroycle such as pyrazole, pyrimidine, isoxazol, oxadiazol and triazol. In this paper, the group of these amino acids, including β-（isoxazoline-5-on-2-yl）-L-alanlne （BIA） in many spe- cies of the tribe .Vicieae, minosine in Leucacna giauca, lathyrine in several Lathyrus sativs species, quisqualic acid （QA） in Quisqualis indica,β- （pyrazol-l-yl） -L-alanine （BPA） in Citrullus vulgaris , Willardilne in Acacia willardiana and Mimosa asperata, isowillardiine in pea seedlings as well as 1,2,4-triazol-l-yl）-L-alanine （BTA） and fl-（ 3-amino- 1,2,4-triazol-1-yl）-L-alanine （BATA） in higher plants, were＇ reviewed. Emphasis was placed on their distributions, bio- synthesis, and the physiological activities. Finally, aspects of the particularl）, important research on those heteroeyellc non-protein amino acids in the future are discussed.

关 键 词：杂环取代 半胱氨酸合成酶 O-乙酰丝氨酸 生理活性 

分 类 号：Q946[生物学—植物学]