基于因子分析的感冒后咳嗽中医证候研究  

Study on TCM Syndrome of Post-infectious Cough Based on Factor Analysis

作　　者：阎玥[1] 杨璐[2] 宋芊[2] 李文成[2] 李丹阳[2] 李宜通[2] 李友林[1] 

机构地区：[1]中日友好医院,北京100029 [2]北京中医药大学,北京100029

出　　处：《中华中医药学刊》2014年第1期217-219,共3页Chinese Archives of Traditional Chinese Medicine

摘　　要：目的:采用因子分析方法探讨感冒后咳嗽中医证候的分布特点,为指导临床辨证提供科学依据。方法:采用多中心,开放式,有监督与无监督相结合的观察性研究方法,于北京市7所医院共采集419例感冒后咳嗽患者,对所得数据应用SPSS 13.0软件,进行因子分析。结果:临床流行病学调查共筛选得到包括干咳无痰、痰质稀薄、痰量少、咳嗽声低无力、嗓音嘶哑、咽痒、咽部异物感、舌色鲜红、白苔、薄苔、弦脉、细脉等共计64个变量,其中包括47个症状变量和15个舌脉变量。通过对感冒后咳嗽47个常见症状的因子分析,得到19个公因子。证候类别包括有风邪恋肺、肺气虚、风寒袭表、肺热、阴虚、肺卫气虚、痰浊、脾虚、表虚、肝火犯肺、肺肾两虚、肺热津亏;以及不便于归纳为某一证候类型的,如:咳嗽的诱发因素类、咳嗽加重时间类、痰质类和皮肤症状类。结论:本研究借助因子分析方法,通过对19个公因子的分析和整理,归纳出感冒后咳嗽主要涉及的脏腑、证候特点等信息,简化了研究过程,使结果更具客观性。Objective ：To discuss the distribution characteristics of TCM syndrome on post- infectious cough by using factor analysis, and to provide scientific proof for clinical syndrome differentiation. Methods ： Observational study methods of muhicentre, open type with the combination of supervised and unsupervised were adopted. 419 cases of post -infectious cough were collected in 7 hospitals in Beijing. SPSS 13.0 software was applied to analyze the cases by using factor analy- sis. Results：The screening results of clinical epidemiology survey included 64 variables such as cough without sputum, thin sputum, less sputum, cough with faint and low sound, hoarse voice, itchy throat, pharyngeal foreign body sensation, bright red tongue ,white coating,thin coating,wiry pulse and thready pulse, including 47 symptom variables and 15 tongue and pulse variables. 19 common factors were obtained from 47 common symptoms of post - infectious cough via factor a- nalysis. Syndrome classes included wind restraining the lung,lung qi deficiency,wind- cold attacking the lung, accumu- lated heat in lung,yin deficiency, lung- defense qi deficiency ,phlegm- dampness, spleen deficiency,exterior deficiency, liver fire invasion of the lung,lung - kidney deficiency,lung heat and body fluid deficiency, defense qi deficiency. There were some symptoms that did not belong to any classes, such as the class of cough inducing factors, the time of cough ag- gravation, the characteristics of the sputum and the symptoms of the skin. Conclusion ： By adopting factor analysis via analy- sis and settlement of 19 common factors, the research summarized the information such as the mainly referred internal or- gans of post- infectious cough and syndrome characteristics, which simplified the research process and made the results more objective.

关 键 词：感冒后咳嗽 因子分析 证候 症状 临床流行病学 

分 类 号：R511.6[医药卫生—内科学]