^(99m)Tc-MIBI显像定位诊断甲状旁腺功能亢进的临床价值  

Clinical Value of the Localization of Hyperparathyroidism with^(99m)Tc - MIBI Imaging

作　　者：苏新辉[1] 徐竞英[2] 巴建涛[2] 

机构地区：[1]厦门市第一医院核医学科,361003 [2]中国医学科学院中国协和医科大学北京协和医院核医学科

出　　处：《中国医学计算机成像杂志》2000年第5期341-343,共3页Chinese Computed Medical Imaging

摘　　要：目的：评价９９ｍＴｃ－ ＭＩＢＩ显像在定位诊断早状旁腺功能亢进中的价值。材料和方法： ３０例临床诊断或高度怀疑甲旁亢患者于颈部及上胸部行９９ｍＴｃ－ＭＩＢＩ显像，采用双时相法（１５ｍｉｎ即刻相及１２０ｍｉｎ延迟相）并加做９９ｍＴｃ－ＭＩＢＩ全身显像，同期做Ｂ超（３０例）和ＣＴ检查（１０例）。结果：与手术病理结果对照，９９ｍＴｃ－ＭＩＢＩ显像、Ｂ超和 ＣＴ诊断准确性分别为 ８３．３％、６３．３％和 ７０％，对于正常位置、异位、术后复发，９９ｍＴｃ－ ＭＩＢＩ显像阳性检出率均较Ｂ超、ＣＴ高。结论：９９ｍＴｃ－ＭＩＢI显像在定位诊断甲状旁腺功能亢进疾患具有较高临床价值，尤其对异位和术后复发及确定有无三发性甲旁亢的敏感性优于Ｂ超、ＣＴ，可作为甲状旁腺功能亢进症术前定位诊断的主要手段。Purpose: To evaluate the diagnostic values of 99m To - MIBI imaging in localizing of hyperparathy- roidism. Moterials and Methods:99m To - MIBI double - phase imaging was performed on 30 patients with hyperparathyroidism or highly suspectable hyperparathyroidism for 15 min (early phase imaging) and 2 hours(delayed Phase imaging) at neck and chest, followed by whole body imaging. Meanwhile all the patients had undergone ultrasound and 10 patients with CT. Results: In correlation with surgery and pathology, the accuracies of 99m To - MIBI imaging, ultrasound and CT were 83. 3% , 63. 3%and70% , respectively, Especially in the patients who have had normal position or ectopic hyperparathyroidism anrecurrent hyperparathyroidism, 99m To - MIBI imaging has higher positive rate than ultrasound and CT. Conclusions: There are significant clinical values of the localization of hyperparathyroidism with 99m Tc - MIBI imaging, especially in the ectopic, recurrent or tertiary hyperparathyroidism patients, so 99m Tc- MIBI imaging can be a useful method for the preoperative localization of hyperparathyroidism.

关 键 词：甲亢 锝99M-MIBI 诊断 

分 类 号：R817[医药卫生—影像医学与核医学]