儿童与成人胰腺实性假乳头状瘤临床和MDCT特征的比较  

Solid pseudopapillary tumor of the pancreas in children and adults:clinical and MDCT manifestation

作　　者：胡曙东[1,2] 黄蔚[1] 李卫侠[1] 凌华威[1] 宋琦[1] 柴维敏[1] 陈克敏[1] 

机构地区：[1]上海交通大学医学院附属瑞金医院放射科,上海200025 [2]江苏大学附属人民医院放射科,江苏镇江212002

出　　处：《外科理论与实践》2013年第6期536-539,共4页Journal of Surgery Concepts & Practice

基　　金：国家自然科学基金(81071281;81271740);上海市科委生物医药重点项目(10411953000;11411952000);上海市科委基础重点项目(10JC1410900);卫生行业科研专项项目(201002020)

摘　　要：目的:回顾性分析儿童胰腺实性假乳头状瘤(solid pseudopapillary tumor,SPT)的临床特征及多层螺旋CT(multidetector computed tomography,MDCT)影像学表现,并与成人胰腺SPT进行对照研究。方法:收集2000年1月至2012年12月行MDCT检查且病理确诊为胰腺SPT的102例病人。分析胰腺SPT的症状和CT病变部位、大小、形态、包膜、钙化、内部组成、密度和强化模式。对上述结果进行统计学处理,采用x^2和t检验。结果:共收集患儿18例(≤18岁),成人84例(>18岁)。患儿,男3例,女15例,平均年龄(15.1±1.91)岁,腹痛不适(9/18,50%)为儿童胰腺SPT最主要的临床表现;儿童病变平均直径明显大于成年病人[(9.1±3.8)cm比(5.9+3.2)cm,P=0.000 3];除肿瘤大小外,儿童和成人胰腺SPT的临床和影像学特点均无统计学差异。结论:对于10岁以上的女性儿童,胰腺有较大占位并具有典型SPT的MDCT影像学表现时,应考虑SPT可能。Objective To retrospectively assess the imaging features of muhidetector computed tomography （MDCT） and clinical characteristics of pancreatic solid pseudopapillary tumor （SPT） in children by comparison with adults. Methods From Jan 2000 to Dec 2012, MDCT images of 102 consecutive patients with pancreatic SPT diagnosed with pathology were reviewed. The MDCT imaging features and clinical manifestation were compared using X2 test or t-test. Results There were 18 children （〈18 years old） and 84 adults （〉18 years old） in this study. The mean age was 15.1＋_ 1.91 years for the children group （15 girls and 3 boys）. Abdominal pain or discomfort was the most common manifestation in children group （9/18, 50%）. The mean tumor diameter in children group [（9.1＋_3.8） cm] was significantly larger than that in adults group [（5.9＋_3.2） cm, P=0.000 3]. Beside tumor diameter, no difference in clinical or imaging features was observed between children group and adults group. Conclusions The diagnosis of pancreatic SPT should be considered when large pancreatic mass with MDCT typical imaging features is found in a girl large than 10 year old.

关 键 词：胰腺实性假乳头状瘤 计算机X线体层摄影术 

分 类 号：R735.9[医药卫生—肿瘤]