老年高血压病患者动态血压与颈动脉粥样硬化的关系  

Relationship between ambulatory blood pressure and carotid atherosclerosis in aged patients with hypertension

作　　者：刘润梅[1] 夏云峰[1] 殷亚昕[1] 翟红霞[1] 李良[1] 张津津[1] 王磊[1] 李娜[1] 陈海威[1] 

机构地区：[1]解放军总医院第一附属医院干一科,北京100048

出　　处：《心血管康复医学杂志》2013年第6期569-571,共3页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的:探讨老年高血压病患者动态血压与颈动脉粥样硬化的关系。方法:选择220例年龄大于60岁的老年高血压病患者行动态血压监测,记录24h血压水平、血压变异性、脉压及血压昼夜节律。同时所有患者行颈动脉B超检查,检查颈动脉粥样硬化情况,依据颈动脉内膜中层厚度或是否有动脉粥样硬化斑块分为颈动脉粥样硬化组(142例,占64.5%)和非颈动脉粥样硬化组(78例,35.5%)。结果:与非颈动脉粥样硬化组比较,颈动脉粥样硬化组24h平均收缩压[(124.52±14.46)mmHg比(133.16±13.62)mmHg]、白昼收缩压[(127.23±16.42)mmHg比(136.25±12.44)mmHg],24h平均脉压[(56.74±8.98)mmHg比(64.66±10.20)mmHg]、白昼平均脉压[(56.97±7.23)mmHg比(66.52±14.62)mmHg]夜间平均脉压[(55.61±6.32)mmHg比(63.92±7.42)mmHg]显著升高,24h、白昼、夜间血压变异性也显著升高(P均<0.05)。结论:老年高血压病患者颈动脉粥样硬化发生率高,与动态血压、脉压水平升高,血压变异性、昼夜节律改变有密切关系。Objective： To explore relationship between ambulatory blood pressure and carotid atherosclerosis （AS） in aged patients with hypertension. Methods.. A total of 220 〉60 years aged patients with hypertension received ambulatory blood pressure monitoring （ABPM）. Level of 24h blood pressure, blood pressure variability, pulse pressure and circadian rhythm of blood pressure were recorded. Meanwhile, all patients received carotid artery B type ultra- sonography to detect carotid AS. According to carotid intimamedia thickness （IMT） or atherosclerotic plaques or not, patients were divided into carotid AS group （n = 142, 64.5%） and non carotid AS group （n = 78, 36. 5%）. Resuits.. Compared with non carotid AS, there were significant increase in 24h mean systolic blood pressure [24hSBP, （124. 52 ± 14. 46） mmHg vs. （133.16 ± 13.62） mmHg], daytime SBP [ （127.23 ± 16.42） mmHg vs. （136. 25 ± 12.44） mmHg], mean24h pulse pressure [24h PP （56.74±8.98） mmHg vs. （64.66± 10.20） mmHg] , day PP [dPP （56.97±7.23） mmHgvs. （66.52±14.62） mmHg], night PP [nPP （55.61±6.32） mmHgvs. （63.92± 7.42） mmHg], and standard deviations of 24h, daytime, nighttime SBP in carotid AS group, P〈0.05 all. Conclusion： Incidence rate of carotid atherosclerosis is high in aged patients with hypertension, and it＇s closely related to ambulatory blood pressure, pulse pressure level, and blood pressure variability, circadian rhythm change.

关 键 词：老年人 高血压 血压 便携式 颈动脉疾病 

分 类 号：R544.109[医药卫生—心血管疾病]