基于检测铜离子的香豆素水合肼希夫碱荧光探针的研究  

Study on a coumarin hydrazine schiff base fluorescent probe for copper ion detection

作　　者：申有名[1,2] 李林[1] 陈超男[1] 刘敏迪 奉少东 赵菁[1] 张向阳[1] 郑清云[1] 张春香[1] 

机构地区：[1]湖南文理学院化学化工学院,湖南常德415000 [2]湖南师范大学化学生物学及中药分析教育部重点实验室,湖南长沙410081

出　　处：《湖南文理学院学报（自然科学版）》2013年第4期17-20,59,共5页Journal of Hunan University of Arts and Science(Science and Technology)

基　　金：湖南省教育厅项目(11C0917);湖南师范大学化学生物学及中药分析教育部重点实验室开放基金(KLCBTC MR 2011-05);湖南文理学院大学生创新项目;湖南文理学院博士启动基金;湖南省十二五重点建设学科--应用化学资助

摘　　要：设计合成了一种基于新型香豆素水合肼希夫碱荧光探针,结构经1H NMR表征.利用荧光光谱研究了该探针分子对铜离子的识别作用.实验表明,该探针对铜离子具有较好的选择性识别能力,加入铜离子后,该探针的荧光发射强度显著减弱,并且荧光发射强度随着Cu2+浓度的增加而减弱.通过荧光离子滴定实验对其选择性和抗干扰能力进行了系统研究,发现加入其他常见金属离子(如Al3+、Ca2+、Co2+、Cr3+、Fe3+、K+、Mg2+、Na+、Ni2+、Zn2+等),荧光强度没有发生变化,并且上述各种离子分别与铜离子共存时,对其没有干扰.结果表明,香豆素水合肼希夫碱荧光探针对铜离子具有较高选择性识别.A novel coumarin derivative was synthesized facilely by the condensation reaction of coumarin and hydrazine hydrate, and its structure was characterized by ^1H NMR. The recognition properties of the target compound 3 with Cu^2＋ had been investigated by the fluorescence spectrophotometry. The results showed that the probe 3 exhibited the selective recognition of Cu^2＋. Upon addition of the concentration of Cu^2＋ to the solution of compound 3, decreasing fluorescence was observed. The selective and interference of compound 3 were discussed. The fluorescence intensity of compound 3 was no chang when the compound 3 was joined other metal ion （such as Al^3＋, Ca^2＋, Co^2＋, Cr^3＋, Fe^3＋. K^＋, Mg^2＋. Na^＋. Ni^2＋, Zn^2＋, etc.）. The interference was found,when other metal and Cu^2＋ coexist in solution of compound 3. Experiments showed that probe 3 was selective recognition of Cu^2＋.

关 键 词：铜离子 香豆素 希夫碱 荧光探针 

分 类 号：O631.3[理学—高分子化学]