氟比洛芬酯超前镇痛对无痛人工流产术麻醉效果及丙泊酚用量的影响  

Effect of flurbiprofen axetil on the anesthetic effect of painless artificial abortion and the dosage of propofol

作　　者：孟朋民[1] 杨泉林[2] 苏心镜[1] 

机构地区：[1]河北北方学院附属第二医院麻醉科,河北宣化075100 [2]河北北方学院附属第二医院妇产科

出　　处：《中国妇幼保健》2014年第1期99-101,共3页Maternal and Child Health Care of China

摘　　要：目的:探讨与观察氟比洛芬酯超前镇痛对无痛人工流产术麻醉效果及丙泊酚用量的影响。方法:选择拟行无痛人工流产的早孕者80例随机分为两组各40例,观察组为氟比洛芬酯配合丙泊酚静脉麻醉,对照组为丙泊酚静脉麻醉。观察两组患者术中及术后BP、HR、SpO2变化及麻醉效果、麻醉剂用量、麻醉后苏醒时间、不良反应等。结果:对照组术中BP下降、HR减慢与术前及观察组比较差异有统计学意义(P<0.05);观察组和对照组丙泊酚应用次数、用量、术后苏醒时间分别为(1.2±0.3)次和(2.2±0.8)次、(112.3±4.5)mg和(172.2±5.6)mg、(4.7±1.4)min和(6.8±2.1)min,差异有统计学意义(P<0.05);观察组麻醉效果Ⅰ级(优)34例,对照组19例,差异有统计学意义(P<0.05)。两组恶心、呕吐、咳嗽、丙泊酚注射痛、术后宫缩痛等不良反应差异均有统计学意义(P<0.05)。结论:氟比洛芬酯超前镇痛能显著提高无痛人工流产术的麻醉效果,减少了丙泊酚次数和用量,缩短了麻醉后苏醒时间,降低了麻醉并发症或药物不良反应的发生率,提高了无痛人工流产术的安全性。Objective： To explore the effect of flurbiprofen axetil preemptive analgesia on the anesthetic effect of painless artificial abortion and the dosage of propofol. Methods： 80 cases of early pregnancy patients who planned to select painless artificial abortion were se- lected and divided into two groups （ n = 40） . Patients in observation group were given flurbiprofen axetil combined with propofol intravenous anesthesia and patients in control group were given propofol intravenous anesthesia. BP, HR, SpO2, anesthetic effect, dosage of anesthetic, recovery time after anesthesia, side effects were detected. Results： Compared with before operation and observation group, there was significant difference in BP of patients in control group during operation （P 〈 0. 05） . There were significant differences in propofo] application times, propofol dose, recovery time after anesthesia between observation and control groups （P 〈 0. 05） . There was significant difference in I grade anesthetic effect between observation and control groups （P 〈 0. 05 ） . There were significant differences in nausea, vomiting, coughing, propofol injection pain, uterine contraction pain after operation between observation and control groups （P 〈 0. 05） . Conclusion： Flurbiprofen axetil preemptive analgesia can increase the anesthetic effect of painless artificial abortion, decrease the times and dose of propofol, shorten recovery time after anesthesia, reduce the anesthetic complications or drug side effects, increase the safety of painless artificial abortion.

关 键 词：无痛人工流产术 氟比洛芬酯 超前镇痛 丙泊酚 麻醉效果 

分 类 号：R714.21[医药卫生—妇产科学]